Practice of Pharmaceutical Care Network Europe Classification System for Proton Pump Inhibitors-Related Problems in Outpatient and Emergency Departments

ZHANG Ying; LIANG Yongchao; RAN Li; GU Qing; LIU Lihong; WANG Huaguang

doi:10.14009/j.issn.1672-2124.2022.10.024

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Practice of Pharmaceutical Care Network Europe Classification System for Proton Pump Inhibitors-Related Problems in Outpatient and Emergency Departments

更新时间：2023-04-16

- Practice of Pharmaceutical Care Network Europe Classification System for Proton Pump Inhibitors-Related Problems in Outpatient and Emergency Departments
- Vol. 22, Issue 10, Pages: 1264-1267(2022)
- 作者机构：
  
  1. 首都医科大学附属北京朝阳医院药事部
  2. 中日友好医院药学部
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2022.10.024
  CLC： R95
- Published：2022，
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ZHANG Ying, LIANG Yongchao, RAN Li, et al. Practice of Pharmaceutical Care Network Europe Classification System for Proton Pump Inhibitors-Related Problems in Outpatient and Emergency Departments. [J]. 22(10):1264-1267(2022)
DOI：

ZHANG Ying, LIANG Yongchao, RAN Li, et al. Practice of Pharmaceutical Care Network Europe Classification System for Proton Pump Inhibitors-Related Problems in Outpatient and Emergency Departments. [J]. 22(10):1264-1267(2022) DOI： 10.14009/j.issn.1672-2124.2022.10.024.

摘要

目的：探索利用欧洲药学监护联盟(PCNE)分类体系处理门急诊患者质子泵抑制剂(PPI)药物相关问题(DRP)的应用与实践，为门急诊PPI的规范化应用提供依据及实践模式。方法：收集2020年1—6月首都医科大学附属北京朝阳医院(西院)门急诊PPI处方，利用处方前置审核软件与药师人工药学服务相结合的方式识别DRP并进行干预，依据PCNE分类体系识别PPI药物相关问题并进行统计分析。结果：在6 044例使用PPI的门急诊患者中，发现451例药物相关问题，均进行了干预，干预接受421例，干预接受率为93.35%。“治疗效果不佳”(27.27%

123/451)、“(可能)发生药品不良事件”(29.93%

135/451)和“不必要的药物治疗”(42.79%

193/451)为DRP常见问题；同一DRP可能存在多个具体原因(原因总例数为543例)

其中药物选择类别(57.46%

312/543)为问题发生的主要原因。结论：DRP分类体系可提升药师识别、处理DRP的能力，准确发现引起DRP的原因，对审核处方规则规范化、药学服务工作记录标准化和DRP综合分析系统化具有重要意义。

Abstract

OBJECTIVE: To explore the application and practice of pharmaceutical care network Europe（PCNE） classification system for proton pump inhibitors（PPI） drug-related problems（DRP） in outpatient and emergency department

so as to provide basis and practice mode for standardized application of PPI in outpatient and emergency departments. METHODS: The PPI prescriptions of outpatient and emergency departments were collected from Beijing Chaoyang Hospital（West Ward） Affiliated to Capital Medical University from Jan. to Jun. 2020

DRP were identified and intervened by the combination of Prescription Pre-review Software and manual pharmaceutical care

and PPI drug-related problems were identified and statistically analyzed based on the PCNE classification system. RESULTS: Among 6 044 cases of outpatients and emergency patients using PPI

451 cases of drug-related problems were identified

all of which were intervened

with 421 intervention acceptances and a 93.35% intervention acceptance rate. “Poor treatment outcome”（27.27%

123/451）

“（possible） adverse drug events”（29.93%

135/451） and “unnecessary drug therapy”（42.79%

193/451） were common DRP problems; one problem could have more causes（the total number of causes was 543）

among which the drug selection category（57.46%

312/543） was the main reason for the problem. CONCLUSIONS: DRP classification system can improve pharmacists’ ability to identify and deal with DRP and accurately discover the causes of DRP

which is of great significance for the normalization of rules of prescription audit

standardization of records of pharmaceutical care and systematization of comprehensive analysis of DRP.

关键词

药物相关问题欧洲药学监护联盟处方前置审核药学服务

Keywords

Drug-related problemsPharmaceutical care network EuropePrescription pre-reviewPharmaceutical care

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