Progress of Kidney Function-Based Clinical Decision Support System for Rational Drug Use

WANG Jin; LI Chen; CHEN Mengli

doi:10.14009/j.issn.1672-2124.2022.08.026

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Progress of Kidney Function-Based Clinical Decision Support System for Rational Drug Use

更新时间：2023-04-16

- Progress of Kidney Function-Based Clinical Decision Support System for Rational Drug Use
- Vol. 22, Issue 8, Pages: 1014-1016(2022)
- 作者机构：
  
  1. 解放军医学院
  2. 中国人民解放军总医院药剂科
  3. 中国人民解放军总医院转化医学研究中心
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2022.08.026
  CLC： R969.3
- Published：2022，
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WANG Jin, LI Chen, CHEN Mengli. Progress of Kidney Function-Based Clinical Decision Support System for Rational Drug Use. [J]. 22(8):1014-1016(2022)
DOI：

WANG Jin, LI Chen, CHEN Mengli. Progress of Kidney Function-Based Clinical Decision Support System for Rational Drug Use. [J]. 22(8):1014-1016(2022) DOI： 10.14009/j.issn.1672-2124.2022.08.026.

摘要

慢性肾脏病患者由于肾功能降低，药物代谢及排泄减慢，发生用药差错及不良反应事件的风险增加，这对临床医师在选择药物及确定药物剂量方面提出了更高的要求。目前，临床决策支持系统(CDSS)已被广泛应用于减少药物差错、提高药物安全性，为辅助医师基于患者肾功能水平进行用药决策提供了新思路。本文旨在对基于肾功能水平CDSS的构建方式、有效性验证、不足及优化等方面进行综述，为构建高效的基于肾功能水平的CDSS提供参考。

Abstract

Patients with chronic kidney disease are at increased risk of medication errors and adverse events due to decreased renal function

slowed drug metabolism and excretion

which puts forward higher requirements for clinicians in drug selection and drug dose determination. At present

clinical decision support system（CDSS） has been widely used to reduce drug errors and improve drug safety

providing a new idea for assisting clinicians to make drug decisions based on patients’ renal function level. This paper aims to review the construction methods

validation

deficiencies and optimization of CDSS based on renal function level

and provide reference for constructing efficient CDSS based on renal function level.

关键词

临床决策支持系统肾功能用药差错

Keywords

Clinical decision support systemRenal functionMedication errors

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Related Institution

Dept. of Cardiovascular Medicine, Huai’an First People’s Hospital/the Affiliated Huai’an No.1 Hospital of Nanjing Medical University

Dept.of Pharmacy, Medical Security Center, General Hospital of PLA

Dept.of Urology,the Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine

Dept.of Orthopedics,Shanghai Fengxian District Central Hospital

Dept.of Pharmacy, the Third Affiliated Hospital of Soochow University

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