Investigation on Current Status of Prophylactic Medication for Stress Ulcer During Perioperative Period in China

LI Zhe; LI Dandan; WEN Aiping; SHEN Su

doi:10.14009/j.issn.1672-2124.2022.02.025

您当前的位置：

首页 >

文章列表页 >

Investigation on Current Status of Prophylactic Medication for Stress Ulcer During Perioperative Period in China

更新时间：2022-10-08

- Investigation on Current Status of Prophylactic Medication for Stress Ulcer During Perioperative Period in China
- Vol. 22, Issue 2, Pages: 232-236(2022)
- 作者机构：
  
  首都医科大学附属北京友谊医院西药剂科
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2022.02.025
  CLC： R969
- Published：2022，
扫描看全文
LI Zhe, LI Dandan, WEN Aiping, et al. Investigation on Current Status of Prophylactic Medication for Stress Ulcer During Perioperative Period in China. [J]. 22(2):232-236(2022)
DOI：

LI Zhe, LI Dandan, WEN Aiping, et al. Investigation on Current Status of Prophylactic Medication for Stress Ulcer During Perioperative Period in China. [J]. 22(2):232-236(2022) DOI： 10.14009/j.issn.1672-2124.2022.02.025.

摘要

目的：考察我国围手术期应激性溃疡预防用药的相关情况。方法：检索中国知网、万方数据库、维普数据库和中国生物医学文献数据库中涉及围手术期预防应激性溃疡情况调查的临床研究，检索时间为不同期刊的创刊时间至2020年12月3日，阅读全文，对纳入的研究进行相关资料提取和统计分析。结果：共纳入36项研究，涉及22 624例外科患者，其中进行应激性溃疡预防用药的患者共17 865例。18项研究考察了应激性溃疡预防用药率，其中应激性溃疡预防用药率为49.29%(4 539/9 208);29项研究评价了应激性溃疡预防用药是否符合相关指征，无指征预防用药率为51.90%(6 758/13 020);19项研究评价了应激性溃疡预防用药的合理性，不合理用药率为72.68%(8 329/11 460)。结论：我国围手术期预防应激性溃疡存在大量过度预防用药的情况，并且存在用药不合理现象。

Abstract

OBJECTIVE: To investigate the relevant situation of prophylactic medication of stress ulcer during perioperative period in China. METHODS: CNKI

Wanfang Data

VIP database and CBM were retrieved to collect the clinical studies related to prophylactic medication for stress ulcer during perioperative period. The retrieval time was from the establishment of different journals to Dec. 3 rd

2020. The relevant information was extracted and statistically analyzed for the included studies after reading the full text. RESULTS: A total of 36 studies were enrolled

including 22 624 surgical patients

of which totally 17 865 patients underwent stress ulcer prophylaxis. The rate of prophylactic medication for stress ulcer was 49.29%（4 539/9 208）in 18 studies. Twenty-nine studies evaluated stress ulcer prophylaxis for relevant indications

with an unindicated prophylaxis rate of 51.90%（6 758/13 020）. Nineteen studies evaluated the rationality of prophylactic medication for stress ulcer

and the irrational medication rate was 72.68%（8 329/11 460）. CONCLUSIONS: There is a large amount of over-prophylaxis in the prevention of stress ulcers in the perioperative period in China

with irrational drug use phenomenon.

关键词

应激性溃疡围手术期质子泵抑制剂H2受体拮抗剂

Keywords

Stress ulcerPerioperative periodProton pump inhibitorH2 receptor antagonist

references

查看原文

Views

278

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effects of Clinical Pathway of Drug Therapy on Management of Prophylactic Use of Proton Pump Inhibitors in Head and Neck Surgery During Perioperative Period

Analysis on Application of Proton Pump Inhibitors in Bozhou People’s Hospital in 2018 Based on Daily Defined Dose Method and ABC-Improved VEN Method

Related Author

DONG Yueyan

XIE Yue

HAN Furong

ZHANG Chao

WANG Haikun

WANG Jie

WU Na

ZENG Cheng

Related Institution

Dept. of Pharmacy, Beijing Tongren Hospital, Capital Medical University

Dept.of Pharmacy, Bozhou People’s Hospital

School of Traditional Chinese Medicine, Bozhou University

⁰