OBJECTIVE: To probe into the application effects of experiential education of complication in improving medication literacy

medication adherence and medication compliance in patients with atrial fibrillation.METHODS: Simple random sampling method was used to select 90 patients with atrial fibrillation admitted into the cardiovascular department of Medicine of the First Affiliated Hospital of University of Science and Technology of China from Jan. to May 2020 as study subjects

and all patients were randomly divided into observation group（ 45 cases） and control group（ 45 cases）. The control group was given routine health education for patients with atrial fibrillation during hospitalization

while the observation group were given experiential health education of complication based on the control group. Scores of medication literacy scale and Morisky medication adherence scale

and medication compliance rates at 1

3 and 6 months after discharge were assessed and compared between two groups before and after the intervention. RESULTS: There were no statistical significance in differences in scores of medication literacy scale and Morisky medication adherence scale between two groups before intervention（ P > 0. 05）; after intervention（ at discharge）

the scores of medication literacy scale and Morisky medication adherence scale of the observation group were significantly better than those of the control group

and the medication adherence rates at 1

3 and 6 months after discharge were significantly higher than those of the control group

with statistically significant differences（ P < 0. 05）.CONCLUSIONS: Compared with conventional health education

the experiential health education of complications can effectively improve the medication literacy and medication adherence of patients with atrial fibrillation

regulate patients’ poor medicine-taking behavior

and improve their medication compliance rate.