Research on Influencing Factors and Crisis Management Measures of Potentially Inappropriate Medication in Elderly Patients in Cardiology

WANG Xingdong; WANG Nan; SONG Juan

doi:10.14009/j.issn.1672-2124.2021.09.025

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Research on Influencing Factors and Crisis Management Measures of Potentially Inappropriate Medication in Elderly Patients in Cardiology

更新时间：2022-10-08

- Research on Influencing Factors and Crisis Management Measures of Potentially Inappropriate Medication in Elderly Patients in Cardiology
- Vol. 21, Issue 9, Pages: 1128-1131(2021)
- 作者机构：
  
  中国人民解放军东部战区总医院药剂科
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2021.09.025
  CLC： R969
- Published：2021，
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WANG Xingdong, WANG Nan, SONG Juan. Research on Influencing Factors and Crisis Management Measures of Potentially Inappropriate Medication in Elderly Patients in Cardiology. [J]. 21(9):1128-1131(2021)
DOI：

WANG Xingdong, WANG Nan, SONG Juan. Research on Influencing Factors and Crisis Management Measures of Potentially Inappropriate Medication in Elderly Patients in Cardiology. [J]. 21(9):1128-1131(2021) DOI： 10.14009/j.issn.1672-2124.2021.09.025.

摘要

目的:了解老年心内科患者潜在不适当用药(potentially inappropriate medication

PIM)情况及影响因素

探讨老年心内科患者的用药危机管理措施。方法:随机选取2019年8月至2020年11月中国人民解放军东部战区总医院心内科收治300例老年患者。依据STOPP/START标准(2014版)评估患者PIM情况

采用Logistic回归分析老年心内科患者PIM的影响因素。结果:纳入的300例患者中

存在PIM者共235例

PIM涉及STOPP标准104例次、START标准271例次

存在合并多个STOPP/START标准的PIM情况;单因素分析结果显示

患者年龄、罹患疾病数、联合用药品种数、心血管疾病史以及是否接受抗栓治疗与老年心内科患者PIM的发生存在相关性(P<0.05); Logistic回归分析结果显示

心房颤动、稳定型心绞痛、冠状动脉粥样硬化、联合用药和抗栓治疗是导致PIM的危险因素(P<0.05)。结论:老年心内科患者PIM的影响因素主要包括心房颤动、稳定型心绞痛、冠状动脉粥样硬化、联合用药(11～21种)及抗栓治疗

采取规范药品的分类与存放、根据STOPP/START标准完善心内科用药以及规范心内科用药流程等用药危机管理措施对于降低老年心内科患者的PIM风险具有积极意义。

Abstract

OBJECTIVE: To investigate the potentially inappropriate medication（ PIM） and influencing factors in elderly patients in cardiology

and to explore the medication crisis management measures for elderly patients in cardiology. METHODS: A total of 300 elderly patients were randomly selected from the cardiology department of General Hospital of Eastern Theater Command of Chinese People’s Liberation Army from Aug. 2019 to Nov. 2020.PIM was evaluated according to STOPP/START criteria（ 2014 Edition）

and the influencing factors of PIM in elderly patients in cardiology were analyzed by Logistic regression. RESULTS: Among the 300 patients

there were 235 cases of PIM

104 case-times with STOPP criteria and 271 case-times with START criteria

and there were cases of PIM combined with multiple STOPP/START criteria. Univariate analysis showed that age

number of diseases

drug combination

history of cardiovascular diseases and antithrombotic therapy were correlated with the occurrence of PIM in elderly patients in cardiology（ P <0. 05）. Logistic regression analysis showed that atrial fibrillation

stable angina

coronary atherosclerosis

drug combination and antithrombotic therapy were risk factors for PIM（ P < 0. 05）.CONCLUSIONS: The influencing factors of PIM in elderly patients in cardiology mainly include atrial fibrillation

stable angina

coronary atherosclerosis

drug combination（ from 11 to 21） and antithrombotic therapy. Medication crisis management measures such as standardizing the classification and storage of drugs

improving cardiology medication according to STOPP/START criteria

and standardizing the cardiology medication process are of positive significance in reducing the risk of PIM in elderly patients in cardiology.

关键词

老年患者心血管疾病心内科潜在不适当用药影响因素危机管理

Keywords

Elderly patientsCardiovascular diseasesCardiology departmentPotentially inappropriate medicationInfluencing factorsCrisis management

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