Necessity of Clinical Application and Key Monitoring of Coenzyme Complex for Injection

DU Chunhui; MOU Jinsong; ZHU Hong; ZHAO Yanling; LIU Fengqun

doi:10.14009/j.issn.1672-2124.2021.07.021

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Necessity of Clinical Application and Key Monitoring of Coenzyme Complex for Injection

更新时间：2022-10-08

- Necessity of Clinical Application and Key Monitoring of Coenzyme Complex for Injection
- Vol. 21, Issue 7, Pages: 865-866(2021)
- 作者机构：
  
  1. 中国人民解放军总医院第五医学中心药学部
  2. 中国人民解放军总医院第五医学中心重症医学中心
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2021.07.021
  CLC： R95
- Published：2021，
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DU Chunhui, MOU Jinsong, ZHU Hong, et al. Necessity of Clinical Application and Key Monitoring of Coenzyme Complex for Injection. [J]. 21(7):865-866(2021)
DOI：

DU Chunhui, MOU Jinsong, ZHU Hong, et al. Necessity of Clinical Application and Key Monitoring of Coenzyme Complex for Injection. [J]. 21(7):865-866(2021) DOI： 10.14009/j.issn.1672-2124.2021.07.021.

摘要

目的:了解某传染病专科医院("以下简称"该院")注射用复合辅酶的使用情况

探讨开展辅助用药重点监控的必要性。方法:调取2019—2020年该医疗机构使用过注射用复合辅酶的出院病例共2 065例

随机抽取其中300例(占比约15%)进行点评

对患者的科室分布、适应证、用法与用量、禁忌证、配伍禁忌和辅助用药联合应用品种数进行统计分析。结果:注射用复合辅酶在该医疗机构使用广泛

300例患者中

有109例存在不合理用药(占36.33%)

其中97例为肝病辅助用药联合应用过多;存在配伍禁忌的处方有18种

疗程过长(>30 d)的患者6例

存在禁忌证的患者2例。结论:注射用复合辅酶作为肝病辅助用药存在较多不合理使用情况

有必要加强监控。

Abstract

OBJECTIVE: To investigate the application of coenzyme complex for injection in an infectious disease hospital（ hereinafter referred to as "this hospital"）

and to discuss the necessity of key monitoring of adjuvant drugs.METHODS: A total of 2 065 discharged patients who received coenzyme complex for injection in this hospital from2019 to 2020 were selected

among which 300 cases（ 15%） were randomly selected for review. Statistical analysis was performed on patients ’ department distribution

indications

usage and dosage

contraindications

compatibility contraindications and the number of combined application of adjuvant drugs. RESULTS: Coenzyme complex for injection was widely used in the medical institution. Among the 300 patients

109 cases had irrational drug application（ 36. 33%）

among which 97 cases were off-label application of adjuvant drugs for liver disease. 18 kinds of incompatibility contraindication

6 cases of off-label long treatment course（ > 30 d）

and 2 cases of contraindication.CONCLUSIONS: There are many irrational application of coenzyme complex for injection as adjuvant drugs for liver disease

and it is necessary to strengthen the monitoring.

关键词

注射用复合辅酶辅助用药专项点评重点监控

Keywords

Coenzyme complex for injectionAdjuvant drugsSpecial reviewKey monitoring

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