Distribution and Deposition of Different Gadolinium Contrast Agents in vivo After Magnetic Resonance Imaging Enhancement and Prospect of Herbal Interventions
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Distribution and Deposition of Different Gadolinium Contrast Agents in vivo After Magnetic Resonance Imaging Enhancement and Prospect of Herbal Interventions
WANG Junda, SHAN Xuefeng, LI Yanyan. Distribution and Deposition of Different Gadolinium Contrast Agents in vivo After Magnetic Resonance Imaging Enhancement and Prospect of Herbal Interventions. [J]. 21(6):756-760(2021)
DOI:
WANG Junda, SHAN Xuefeng, LI Yanyan. Distribution and Deposition of Different Gadolinium Contrast Agents in vivo After Magnetic Resonance Imaging Enhancement and Prospect of Herbal Interventions. [J]. 21(6):756-760(2021) DOI: 10.14009/j.issn.1672-2124.2021.06.027.
Distribution and Deposition of Different Gadolinium Contrast Agents in vivo After Magnetic Resonance Imaging Enhancement and Prospect of Herbal Interventions
摘要
钆对比剂增强检查一直以来被认为是较为安全的增强检查方法
但近年来临床逐渐发现钆对比剂会以游离钆离子形式分布、沉积于体内
并可能引起一定的危害
如沉积于肾内可能引起肾源性系统纤维化。随着磁共振成像增强检查率不断升高
钆对比剂的应用会更加广泛
肾源性系统性纤维化
颅内沉积
骨内沉积
皮肤、心脏、肺组织、肝脏及淋巴结等器官内沉积现象会增多
但针对上述现象目前尚无解决方法。中医药对于金属离子过载的疾病有着独特的见解
已被证实能够减低多种金属离子过载现象
今后通过进一步研究
可为减少体内过量钆离子提供有力的帮助。
Abstract
Gadolinium contrast enhancement has been considered a safer enhancement method all long
but in recent years it has gradually been found that gadolinium contrast agent can be distributed and deposited in vivo as free gadolinium ions
which may cause certain hazards
such as deposition in the kidney may cause nephrogenic systemic fibrosis. With the increasing rate of magnetic resonance imaging enhanced examination
the application of gadolinium contrast agent will become more widespread
so that the phenomenon of nephrogenic systemic fibrosis
intracranial deposition
intraosseous deposition
deposition in skin
heart
lung tissue
liver and lymph nodes and other organs will increase
but there is no solution for the above phenomenon yet. Traditional Chinese medicine has unique insights into metal ion overload diseases and has been proven to reduce a variety of metal ion overload phenomena
which may provide powerful help to reduce excess gadolinium ions in vivo through further research in the future.
关键词
钆对比剂体内分布沉积中药干预展望
Keywords
Gadolinium contrast agentDistribution in vivoDepositionTraditional Chinese medicine interventionProspect