OBJECTIVE: To investigate drug application in Beijing Children ’s Hospital Affiliated to Capital Medical University（ hereinafter referred to as "our hospital "）

so as to provide references for delicacy drug management. METHODS: Activity based classification（ ABC） analysis

vital-essential-nonessential（ VEN） analysis and ABC-VEN matrix analysis methods were adopted to analyze the varieties and consumption sum of drugs used by outpatient and inpatient in our hospital from Sept. 2018 to Aug. 2019

inventory turnover analysis and dosage analysis were conducted at the same time. RESULTS: Totally 698 kinds of drugs were used in the outpatient and inpatient in our hospital from Sept. 2018 to Aug. 2019

with the consumption sum of 669 322 100 yuan. Based on ABC analysis

the constitute ratio of varieties of drugs in categories A

B and C were respectively 15. 90%（ 111 kinds）

20. 20%（ 141 kinds） and 63. 90%（ 446 kinds）

the constitute ratio of consumption sum were respectively 79. 85%（ 534 441 300 yuan）

15. 10%（ 101 081 400 yuan） and 5. 05%（ 33 799 400 yuan）. Based on VEN analysis

the constitute ratio of varieties of drugs in categories V

E and N were respectively 35. 10%（ 245 kinds）

54. 44%（ 380 kinds） and 10. 46%（ 73 kinds）

the constitute ratio of consumption sum were respectively 29. 30%（ 196 112 200 yuan）

63. 82%（ 427 185 900 yuan） and 6. 88%（ 46 024 000 yuan）. Combined with ABC-VEN matrix analysis

the highest constituent ratio of varieties was 31. 52%（ 220 kinds） for drugs in CE category

the highest constituent ratio of consumption sum was 51. 76%（ 346 472 000 yuan） for drugs in AE category

the lowest constituent ratio of varieties was 0. 86%（ 6 kinds） for drugs in AN category

and the lowest constituent ratio of consumption sum was 0. 66%（ 4 411 800 yuan） for drugs in CN category. CONCLUSIONS: The upper and lower limits of inventory of partial CV-category and CE-category drugs should be appropriately adjusted to ensure the supply for clinical necessary and reduce the occurrence of drug shortage; there are some key drugs under national control among AE-category and AN-category drugs

reducing their use can not only reduce drug costs

but also help promoting clinical rational medication. Combining ABC analysis with VEN analysis to analyze the drug application in hospitals over a period of time is a scientific method applied to practical work

which can provide data support for the detailed management of drug inventory and clinical rational medication.