Literature Analysis of Hyperkalemia Induced by Tacrolimus

JIANG Aidou

doi:10.14009/j.issn.1672-2124.2021.04.028

您当前的位置：

首页 >

文章列表页 >

Literature Analysis of Hyperkalemia Induced by Tacrolimus

更新时间：2022-10-08

- Literature Analysis of Hyperkalemia Induced by Tacrolimus
- Vol. 21, Issue 4, Pages: 501-504(2021)
- 作者机构：
  
  四川大学华西医院临床药学部(药剂科)
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2021.04.028
  CLC： R969
- Published：2021，
扫描看全文
[1]蒋艾豆.他克莫司致高钾血症的文献分析[J].中国医院用药评价与分析,2021,21(04):501-504.

JIANG Aidou. Literature Analysis of Hyperkalemia Induced by Tacrolimus. [J]. 21(4):501-504(2021)
[1]蒋艾豆.他克莫司致高钾血症的文献分析[J].中国医院用药评价与分析,2021,21(04):501-504. DOI： 10.14009/j.issn.1672-2124.2021.04.028.

JIANG Aidou. Literature Analysis of Hyperkalemia Induced by Tacrolimus. [J]. 21(4):501-504(2021) DOI： 10.14009/j.issn.1672-2124.2021.04.028.

摘要

目的:研究免疫抑制剂他克莫司致高钾血症的发生规律及特点

为临床安全用药提供参考。方法:检索截至2020年9月21日国内外数据库收录的他克莫司致高钾血症的文献进行回顾性研究

对患者的临床资料进行统计分析。结果:他克莫司引发的高钾血症是一种较为常见的电解质紊乱

共筛选出有效个案报道18篇

涉及41例患者。高钾血症的发生可能与药物剂量、移植类型等有关;出现高血钾时

建议及时进行对症处理

减少他克莫司剂量或调整免疫抑制剂治疗方案。结论:临床应用他克莫司时应加强用药监测

以避免和减少高钾血症的发生。

Abstract

OBJECTIVE: To probe into the occurrence and characteristics of hyperkalemia induced by the immunosuppressant tacrolimus

so as to provide references for clinical safe medication. METHODS: Literature of hyperkalemia induced by tacrolimus collected in domestic and foreign databases were retrospectively studied as of Sept.21 st

2020. Clinical data were statistically analyzed. RESULTS: Hyperkalemia induced by tacrolimus was the relatively common electrolyte disorder. A total of 18 valid case reports were screened

including 41 patients. The occurrence of hyperkalemia might be related to the doses of drugs and types of transplantation. When hyperkalemia occurred

it was recommended to carry out symptomatic treatment in time and reduce the dose of tacrolimus or adjust the immunosuppressive treatment regimen. CONCLUSIONS: In order to avoid and reduce the occurrence of hyperkalemia

medication monitoring should be strengthened during the clinical application of tacrolimus.

关键词

他克莫司高钾血症不良反应文献分析

Keywords

TacrolimusHyperkalemiaAdverse drug reactionLiterature analysis

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Literature Analysis of Adverse Drug Reactions and Drug Interaction of Tacrolimus

Comparative Analysis on Adverse Drug Reactions Between Ibuprofen and Acetaminophen

Domestic and Foreign Literature of Adverse Drug Reactions Induced by Tigecycline

Allergic Reactions Induced by Statins

Correlation Between CYP3A5 Gene Polymorphism and Tacrolimus Concentration/Dose Ratio in the Early Postoperative Period After Liver Transplantation

Related Author

ZHANG Bihua

WANG Yang

LIU Dongxue

CHEN Di

HUANG Beibei

CHENG Chuhao

ZHANG Hang

GU Tongtong

Related Institution

Dept.of Pharmacy,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Science,Beijing Key Laboratory of Drug Clinical Risk and Personalized Medication Evaluation

Institution of National Drug Clinical Trails, the Affiliated Hospital of Xuzhou Medical University

School of Pharmacy, Nanjing Medical University

Dept.of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Dept.of Clinical Pharmacy, Jinshan Hospital of Fudan University

⁰