OBJECTIVE: To investigate and application of oral solid preparation in inpatients over 60 years old

so as to provide references for clinical rational medication. METHODS: Totally 18 795 medical orders on medication of oral solid preparation in inpatients over 60 years old in the First Hospital of Jilin University from Jun. 2018 to May 2019 were retrieved

10 583 items were retained after removing repeated medical orders

categories of drugs classified by pharmacological effects

specific drug divided dose status

drug divided dose status of different dosage forms and administration route after divided dose were sequentially analyzed. RESULTS: Totally 7 kinds of 131 categories of drug were involved in the 10 583 medical orders

mainly were medication on cardiovascular disease（ 40 categories

30. 53%）

followed by medication on central nervous system（ 33 categories

25. 19%）; the first drug ranked by numbers of divided dose medical orders was Metoprolol succinate sustained-release tablets

including 5 158 medical orders（ 48. 74%）

mainly were split into 1/2 pieces（ 4 699 medical orders

accounted for 91. 10% of medical orders of Metoprolol succinate sustained-release tablets）; the number of divided dose medical orders of sustained and controlled release preparations and enteric-coated preparations was 5 199（ 49. 13%）

of which 138 were nasogastric dosing（ accounted for 2. 65% of medical orders of sustained and controlled release preparations and enteric-coated preparations）

and 2 were stomach tube infusing（ accounted for 0. 04% of medical orders of sustained and controlled release preparations and enteric-coated preparations）. CONCLUSIONS: The problem of divided dose of oral solid preparation is inevitable in clinical

the drug specifications on the market cannot meet the medication needs of special populations

pharmacists should conduct pharmaceutical monitoring on the accuracy and safety of divided dose of solid preparation to promote clinical rational medication.