Analysis of Drug Administration via Stomach Tube for 100 Patients with Severe Liver Disease

DU Chunhui; SUN Jindan; QU Yang; ZHANG Libing; JIANG Cuiyun; ZHAO Yanling; MU Jinsong

doi:10.14009/j.issn.1672-2124.2021.04.025

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Analysis of Drug Administration via Stomach Tube for 100 Patients with Severe Liver Disease

更新时间：2022-10-08

- Analysis of Drug Administration via Stomach Tube for 100 Patients with Severe Liver Disease
- Vol. 21, Issue 4, Pages: 491-492(2021)
- 作者机构：
  
  1. 解放军总医院第五医学中心药学部
  2. 解放军总医院第五医学中心重症医学中心
  3. 廊坊爱德堡医院药学部
  4. 海南医学院第一附属医院药学部
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2021.04.025
  CLC： R969.3
- Published：2021，
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[1]杜春辉,孙金丹,曲阳,张丽冰,蒋翠云,赵艳玲,牟劲松.100例肝病重症患者管饲给药情况分析[J].中国医院用药评价与分析,2021,21(04):491-492+496.

DU Chunhui, SUN Jindan, QU Yang, et al. Analysis of Drug Administration via Stomach Tube for 100 Patients with Severe Liver Disease. [J]. 21(4):491-492(2021)
[1]杜春辉,孙金丹,曲阳,张丽冰,蒋翠云,赵艳玲,牟劲松.100例肝病重症患者管饲给药情况分析[J].中国医院用药评价与分析,2021,21(04):491-492+496. DOI： 10.14009/j.issn.1672-2124.2021.04.025.

DU Chunhui, SUN Jindan, QU Yang, et al. Analysis of Drug Administration via Stomach Tube for 100 Patients with Severe Liver Disease. [J]. 21(4):491-492(2021) DOI： 10.14009/j.issn.1672-2124.2021.04.025.

摘要

目的:了解肝病重症患者管饲给药的药物使用情况

为临床合理管饲给药提供参考。方法:采用回顾性调查方法

对2020年入住某医疗机构肝病重症监护室的100例患者管饲给药情况及其合理性进行评价与分析。结果:100例肝病重症患者管饲给药共4 917例次

涉及99种药物

不合理用药合计544例次

不合理用药率为11.06%

其中药物剂型选择不适宜424例次

联合用药不适宜120例次。主要存在的问题包括研碎易崩解的致癌、细胞毒性药物;将肠溶制剂、缓控释制剂研碎后管饲给药;软胶囊管饲给药剂量不准确;微生态药物与抗菌药物联合应用等。结论:临床管饲给药存在不合理情况

临床药师利用药学专业知识进行适当干预

可促进管饲给药的合理性

提高药物治疗的有效性和安全性。

Abstract

OBJECTIVE: To investigate the status of drug administration via stomach tube for patients with severe liver disease

so as to to provide reference for the rational drug use through feeding tubes in clinic. METHODS:Retrospective investigation method was adopted to evaluate and analyze the rationality of tube feeding administration in100 patients admitted into liver disease of intensive care unit in a medical institution in 2020. RESULTS: 100 patients of severe liver disease received tube feeding for 4 917 case-times

including 99 kinds of drugs. There were544 case-times of irrational drug use

and the irrational rate was 11. 06%

including 424 case-times of unsuitable dosage form and 120 case-times of improper drug combination. Issues mainly included the crushing of disintegrating carcinogenic and cytotoxic drugs

crushing of enteric-soluble preparations and slow-controlled release preparations by tube feeding

soft capsules by tube feeding with inaccurate dosage

drug combination of microecological drugs and antibiotics. CONCLUSIONS: There are irrational phenomenon in clinical tube feeding

appropriate intervention by clinical pharmacists with professional knowledge of pharmacy can promote the rationality of tube feeding and improve the effectiveness and safety of drug therapy.

关键词

胃管肝病重症患者临床药师合理用药

Keywords

Stomach tubeLiver deseaseCritically ill patientClinical pharmacistsRational drug use

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