OBJECTIVE: To probe into the clinical efficacy of sodium hyaluronate injection combined with anterior repositioning splint in the treatment of temporomandibular joint disc displacement. METHODS: Totally 136 patients with temporomandibular joint disc displacement admitted into Beijing Friendship Hospital

Capital Medical University from Aug.2015 to Jun. 2019 were extracted to be randomly divided into the control group and the research group（ 68 cases in each）.The control group was treated with anterior repositioning splint

while the research group received sodium hyaluronate injection in the upper cavity combined with anterior repositioning splint. The degree of joint pain

maximum opening degree and Fricton indicator were observed before treatment and after treatment of 12 weeks. The clinical efficacy was evaluated.RESULTS: Degree of joint pain [visual analogue scale（ VAS） ]: The joint pain in the research group was significantly relieved after treatment of 12 weeks

and the VAS score was significantly better than that of the control group

the difference was statistically significant（ P = 0. 04）. Maximum opening degree: The maximum opening degree in the research group was significantly improved after treatment of 12 weeks

and the effect was better than that in the control group

the difference was statistically significant（ P = 0. 03）. Fricton indicator: Fricton indicator in the research group was significantly better than that in the control group after treatment of 12 weeks

the difference was statistically significant（ P < 0. 01）. Clinical efficacy: After treatment of 12 weeks

the total effective rate in the research group was 88. 24%（ 60/68）

significantly better than that in the control group 73. 53%（ 50/68）

the difference was statistically significant（ P = 0. 029）. CONCLUSIONS:The clinical efficacy of sodium hyaluronate injection combined with anterior repositioning splint in the treatment of temporomandibular joint disc displacement is significant

and the treatment method is simple.