OBJECTIVE: To probe into the clinical efficacy of self-made traditional Chinese medicine decoction in the treatment of radiation proctitis induced by radiotherapy of cervical cancer.METHODS: A total of 120 patients admitted to Chongqing University Cancer Hospital from Sept.2017 to Mar.2020 were randomly divided into the the traditional Chinese medicine treatment group and the control group

with 60 cases in each group.The traditional Chinese medicine treatment group was given self-made traditional Chinese medicine decoction（ pueraria lobata 30 g

scutellaria baicalensis 30 g

coptis chinensis 30 g

pulsatillae radix 30 g

sanguisorbae radix 15 g

flos sophorae 15 g

calculus bovis sativus 300 mg

herba violae 15 g）

while the control group received western medicine（ 160 000 U of gentamicin

5 mg of dexamethasone

4 ml of 2% lidocaine

100 ml of 0.9% sodium chloride injection）.Patients in both groups took 10 d as a course of treatment

with a total of 2 courses of treatment.Symptom score

rectal radiation injury grade

Karnofsky score and the incidence of adverse reactions before and after treatment were observed in two groups.RESULTS: The symptom scores of the traditional Chinese medicine treatment group [abdominal pain/discomfort:（ 0.39±0.19） scores; diarrhea:（ 0.57±0.13） scores

; stool characteristics:（ 0.47 ± 0.26） scores; mucinous bloody stools:（ 0.89 ± 0.14） scores] were significantly lower than those of the control group[abdominal pain/discomfort:（ 1.23±0.22） scores; diarrhea:（ 1.03±0.41） scores; stool characteristics:（ 1.33±0.18） scores; mucinous bloody stools:（ 2.01 ± 0.31） scores]

the differences were statistically significant（ P < 0.05）.Compared with the control group（ 12 cases of grade 0

22 cases of grade Ⅰ

20 cases of grade Ⅱ and 6 cases of grade Ⅲ）

rectal radiation injury classification of patients in the traditional Chinese medicine treatment group after treatment（ 24 cases of grade 0

26 cases of grade Ⅰ

10 cases of grade Ⅱ

0 cases of grade Ⅲ） was significantly improved

and the differences were statistically significant（ P<0.05）.Karnofsky score after treatment in the traditional Chinese medicine treatment group was（ 85.98 ± 7.02） scores

significantly better than（ 65.01 ± 3.22） scores after treatment in the control group

and the differences were statistically significant（ P<0.05）.There were no adverse drug reactions during the treatment in the traditional Chinese medicine treatment group and the control group.CONCLUSIONS: The efficacy of self-made traditional Chinese medicine decoction in the treatment of radiation proctitis induced by radiotherapy of cervical cancer is significant.