OBJECTIVE: To investigate the rational application of compound amino acid injection（ 6 AA） in a tumor hospital（ hereinafter referred to as "this hospital"） before and after pharmacists’ intervention

and to explore the intervention effects. METHODS: Retrospective investigation method was used to extract 100 hospital discharge medical records in this hospital from Jan. to Mar. 2019（ before intervention） and from Oct. to Dec. 2019（ after intervention）. Contrastive analysis was carried out on indications

usage and dosage and solvent. RESULTS: The irrational application rate of compound amino acid injection（ 6 AA） decreased from 80%（ 80/100） before intervention to 56%（ 56/100） after intervention

and the difference was statistically significant（ P<0. 05）.Before intervention

the irrational application of compound amino acid injection（ 6 AA） was found in indications

usage and dosage

and solvent.After continuous intervention by pharmacists

the above irrational application of compound amino acid injection（ 6 AA） was improved

especially in usage and dosage and solvent

with statistically significant difference compared with before intervention（ P<0. 05）.Analysis of irrational indications showed that it mainly concentrated in perioperative nutritional support

followed by perichemotherapy nutritional support and periradiotherapy nutritional support

and the difference before and after intervention was not statistically significant（ P > 0. 05）. CONCLUSIONS: The continuous intervention of pharmacists helps to promote the rational application of compound amino acid injection（ 6 AA）.