OBJECTIVE: To investigate the application status of Polygoni Multiflori Caulis

Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparata in outpatient and inpatient department of Longhua Hospital Shanghai University of Traditional Chinese Medicine（ hereinafter referred to as "our hospital"） from 2019 to 2020

so as to promote the rational drug use and improve the drug safety.METHODS: A total of 207 398 prescriptions for outpatients and inpatients from 2019 to 2020 were extracted by HIS system of our hospital. The prescription analysis system PA software（ software registration number: 2017 SR012498） developed by our hospital was used to perform prescription review on the users

indications

departments

usage and dosage and the incidence of adverse drug reactions of Polygoni Multiflori Caulis

Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparata. Evaluation results were statistically analyzed to judge the rationality of medication. RESULTS: The use of Polygoni Multiflori Caulis was the most

followed by Polygoni Multiflori Radix Preparata and Polygoni Multiflori Radix. In the outpatient department

there were 163 327 prescriptions of Polygoni Multiflori Caulis

which was about 4. 5 times of the prescriptions of Polygoni Multiflori Radix Preparata（ 36 278 prescriptions）

and about 1 349 times of the prescriptions of Polygoni Multiflori Radix（ 121 prescriptions）.In the inpatient ward

there were 6 251 prescriptions of Polygoni Multiflori Caulis

which was about 4. 4 times of the prescriptions of Polygoni Multiflori Radix Preparata（ 1 421 prescriptions）. Polygoni Multiflori Caulis and Polygoni Multiflori Radix Preparata were mostly used in oncology department

which was consistent with the efficacy of both. Polygoni Multiflori Radix was mostly used in specialist clinics and rheumatology department

which reflected that the clinical use of Polygoni Multiflori Radix was more cautious and was consistent with its efficacy. Polygoni Multiflori Caulis

Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparata all had different degrees of overdose use. The drug use in outpatient and inpatient department was basically the same. The incidence of liver injury induced by Polygoni Multiflori Caulis

Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparata were all less than 1%

which was the occasional adverse drug reaction.CONCLUSIONS: The root and vine of Polygonum multiflorum Thunb.can be safely used under the conditions of paying attention to syndrome differentiation and treatment

mastering the dosage

compatibility of drugs

not using for a long time

no abuse and not using for patients with liver disease history.