Analysis of Clinical Dose and Application of Schisandrae Chinensis Fructus Based on Outpatient Prescriptions from 6 Traditional Chinese Medicine Grade Ⅲ,Level A Hospitals in Beijing

GUO Hongye; MU Fangyuan; LI Luyang; FAN Zheng; MEI Na; YU Dian; FAN Liqin; HAO Tingting; LYU Wei; GUO Guiming; WANG Jinghong; CAO Junling; HUA Guodong; KONG Xiangwen; MA Hong; LI Peihong

doi:10.14009/j.issn.1672-2124.2021.02.023

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Analysis of Clinical Dose and Application of Schisandrae Chinensis Fructus Based on Outpatient Prescriptions from 6 Traditional Chinese Medicine Grade Ⅲ,Level A Hospitals in Beijing

更新时间：2022-10-08

- Analysis of Clinical Dose and Application of Schisandrae Chinensis Fructus Based on Outpatient Prescriptions from 6 Traditional Chinese Medicine Grade Ⅲ,Level A Hospitals in Beijing
- Vol. 21, Issue 2, Pages: 223-226(2021)
- 作者机构：
  
  1. 中国中医科学院西苑医院药学部
  2. 北京中医药大学东方医院药学部
  3. 首都医科大学附属北京中医医院药学部
  4. 中国中医科学院望京医院药学部
  5. 北京中医药大学第三附属医院药学部
  6. 北京中医药大学附属护国寺中医医院药学部
  7. 北京中医药大学东直门医院药学部
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2021.02.023
  CLC： R288
- Published：2021，
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[1]郭红叶,穆芳园,李璐瑒,范峥,梅娜,于典,范丽琴,郝婷婷,吕薇,郭桂明,王景红,曹俊岭,华国栋,孔祥文,马红,李培红.基于北京市6家三级甲等中医医院门诊处方数据分析五味子的临床剂量及应用情况[J].中国医院用药评价与分析,2021,21(02):223-226.

GUO Hongye, MU Fangyuan, LI Luyang, et al. Analysis of Clinical Dose and Application of Schisandrae Chinensis Fructus Based on Outpatient Prescriptions from 6 Traditional Chinese Medicine Grade Ⅲ,Level A Hospitals in Beijing. [J]. 21(2):223-226(2021)
[1]郭红叶,穆芳园,李璐瑒,范峥,梅娜,于典,范丽琴,郝婷婷,吕薇,郭桂明,王景红,曹俊岭,华国栋,孔祥文,马红,李培红.基于北京市6家三级甲等中医医院门诊处方数据分析五味子的临床剂量及应用情况[J].中国医院用药评价与分析,2021,21(02):223-226. DOI： 10.14009/j.issn.1672-2124.2021.02.023.

GUO Hongye, MU Fangyuan, LI Luyang, et al. Analysis of Clinical Dose and Application of Schisandrae Chinensis Fructus Based on Outpatient Prescriptions from 6 Traditional Chinese Medicine Grade Ⅲ,Level A Hospitals in Beijing. [J]. 21(2):223-226(2021) DOI： 10.14009/j.issn.1672-2124.2021.02.023.

摘要

目的:基于北京市医疗机构中药饮片处方质量指标监测平台收集的处方数据

探讨五味子在临床的使用剂量及应用规律。方法:通过2018年北京市医疗机构中药饮片处方质量指标监测平台

收集北京市6家三级甲等中医医院门诊含五味子的内服处方

建立数据库

采用Excel 2010软件统计五味子使用剂量频次、频率、主治分布、配伍药物分类和比例等数据

对其基本用药剂量及配伍结构规律进行分析。结果与结论:五味子总使用频次为12 417次

目前临床上五味子的常用剂量范围为6～12 g

常用剂量为10 g（5 967次

占48.06%）、6 g（3 248次

占26.16%）;其中儿童常用剂量为6 g。五味子主治疾病主要为肺系疾病

其次为心系疾病。处方中共涉及到745味中药

其中与五味子配伍频次较高的药物有183味

可分为16类

配伍使用频次排序居前3位的为补虚类、清热类和解表类。五味子与其常配伍中药的剂量比例以1∶1为多

数据分析结果较客观地反映了北京地区6家中医医疗机构中五味子的临床应用规律

可为五味子在临床中的应用以及门诊中药饮片处方点评提供参考。

Abstract

OBJECTIVE: To investigate the clinical dose and application rule of Schisandrae chinensis fructus based on the prescription data collected by monitoring platform for traditional Chinese medicine decoction pieces in medical institutions in Beijing.METHODS: Through the monitoring platform for traditional Chinese medicine decoction pieces in medical institutions in 2018 in Beijing

internal prescriptions with Schisandrae chinensis fructus in outpatient were collected from 6 traditional Chinese medicine grade Ⅲ

level A hospitals in Beijing. The database was established

and Excel 2010 software was used to calculate the dose frequency

frequency

distribution of main treatment

classification and proportion of compatible drugs of Schisandrae chinensis fructus

and the basic drug dose and compatibility structure rule were analyzed. RESULTS & CONCLUSIONS: The total frequency of Schisandrae chinensis fructus was 12 417 times. The commonly used dose range of Schisandrae chinensis fructus in clinical practice was from 6 to 12 g

the commonly used dose was 10 g（ 5 967 times

48. 06%） and 6 g（ 3 248 times

26. 16%）

and the common dose for children was 6 g.The main diseases of Schisandrae chinensis fructus were lung diseases

followed by heart diseases. A total of 745 traditional Chinese medicines were enrolled in the prescriptions

among which 183 were highly compatible with Schisandrae chinensis fructus

and the compatible drugs could be divided into 16 categories.The top three in the list of compatibility frequency were tonic

heat-clearing and antipyretic drugs.The dose ratio of Schisandrae chinensis fructus and its common traditional Chinese medicine was 1 ∶ 1. The data analysis results objectively reflected the clinical application rule of Schisandrae chinensis fructus in 6 traditional Chinese medicine grade Ⅲ

level A hospitals in Beijing

which could provide reference for the clinical application of Schisandrae chinensis fructus and the prescription review of traditional Chinese medicine decoction piece in outpatient department.

关键词

五味子临床剂量配伍处方分析

Keywords

Schisandrae chinensis fructusClinical doseCompatibilityPrescription analysis

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