Systematic Review of Effect of Simethicone Combined with Polyethylene Glycol Electrolyte Powder for Intestinal Preparation Before Capsule Endoscopy

doi:10.14009/j.issn.1672-2124.2021.02.016

您当前的位置：

首页 >

文章列表页 >

Systematic Review of Effect of Simethicone Combined with Polyethylene Glycol Electrolyte Powder for Intestinal Preparation Before Capsule Endoscopy

更新时间：2022-10-08

- Systematic Review of Effect of Simethicone Combined with Polyethylene Glycol Electrolyte Powder for Intestinal Preparation Before Capsule Endoscopy
- Vol. 21, Issue 2, Pages: 189-194(2021)
- 作者机构：
  
  西南医科大学附属医院普通外科(胃肠)
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2021.02.016
  CLC： R574
- Published：2021，
扫描看全文
[1]徐林霞,宋美璇,李显蓉.西甲硅油联合聚乙二醇电解质散在胶囊内镜检查前肠道准备应用效果的系统评价[J].中国医院用药评价与分析,2021,21(02):189-194.

Systematic Review of Effect of Simethicone Combined with Polyethylene Glycol Electrolyte Powder for Intestinal Preparation Before Capsule Endoscopy. [J]. 21(2):189-194(2021)
[1]徐林霞,宋美璇,李显蓉.西甲硅油联合聚乙二醇电解质散在胶囊内镜检查前肠道准备应用效果的系统评价[J].中国医院用药评价与分析,2021,21(02):189-194. DOI： 10.14009/j.issn.1672-2124.2021.02.016.

Systematic Review of Effect of Simethicone Combined with Polyethylene Glycol Electrolyte Powder for Intestinal Preparation Before Capsule Endoscopy. [J]. 21(2):189-194(2021) DOI： 10.14009/j.issn.1672-2124.2021.02.016.

摘要

目的:系统评价西甲硅油联合聚乙二醇电解质散在胶囊内镜检查前肠道准备的应用效果。方法:计算机检索PubMed、EMBase、Ovid、the Cochrane Library、Web of Science、万方数据库、中国知网、中国生物医学文献数据库以及维普数据库等

检索时间为从建库至2019年12月

筛选西甲硅油联合聚乙二醇电解质散用于胶囊内镜检查前肠道准备的随机对照试验或临床对照研究（研究组患者使用西甲硅油联合聚乙二醇电解质散清洁肠道;对照组患者使用聚乙二醇电解质散清洁肠道）

采用Rev Man 5.3软件进行荟萃分析（Meta分析）。结果:本研究最终纳入文献11篇

其中随机对照试验9篇

临床对照研究2篇;共涉及1 198例患者

其中研究组患者598例

对照组患者600例。Meta分析结果显示

研究组患者的肠道气泡量少于对照组

研究组肠道气泡量为A级患者所占比例明显高于对照组

差异有统计学意义（OR=3.37

95%CI=1.96～5.78

P<0.000 01）;研究组患者的肠道清洁度明显优于对照组

研究组肠道清洁度为1级患者所占比例明显高于对照组

差异有统计学意义（OR=1.48

95%CI=1.06～2.08

P=0.02）;研究组患者胶囊内镜胃通过时间明显长于对照组

差异有统计学意义（MD=3.02

95%CI=0.74～5.30

P=0.009）;两组患者胶囊内镜小肠通过时间比较

差异无统计学意义（P=0.57）。结论:西甲硅油能减少肠道内气泡量

可能改善肠道内清洁度

但不增加胶囊内镜小肠通过时间。

Abstract

OBJECTIVE: To systematically evaluate the application effect of simethicone combined with polyethylene glycol electrolyte powder for intestinal preparation before capsule endoscopy. METHODS: Pub Med

EMBase

Ovid

the Cochrane Library

Web of Science

Wanfang database

CNKI

CBM and VIP database were retrieved to collect the randomized controlled trial or clinical controlled study of simethicone combined with polyethylene glycol electrolyte powder for intestinal preparation before capsule endoscopy（ the study group was given simethicone combined with polyethylene glycol electrolyte powder for intestinal cleaning

the control group was treated with polyethylene glycol electrolyte powder for intestinal cleaning）.The retrieval time was from the establishment of the database to Dec.2019.Rev Man 5. 3 software was used for Meta-analysis.RESULTS: Eleven studies were included in this study

including 9 randomized controlled trials and 2 clinical controlled trials.A total of 1 198 patients were enrolled

with 598 patients in the study group and 600 patients in the control group. Meta-analysis results showed that intestinal bubble volume in the study group was less than that in the control group

and the proportion of patients with grade A intestinal bubble volume in the study group was significantly higher than that in the control group

the difference was statistically significant（ OR = 3. 37

95%CI = 1. 96-5. 78

P < 0. 000 01）. The intestinal cleaning in the study group was significantly better than that in the control group

and the proportion of patients with intestinal cleaning level 1 in the study group was significantly higher than that in the control group

the difference was statistically significant（ OR =1. 48

95% CI = 1. 06-2. 08

P = 0. 02）. The gastric passage time of capsule endoscopy in the study group was significantly longer than that in the control group

and the difference was statistically significant（ MD = 3. 02

95%CI =0. 74-5. 30

P = 0. 009）. There was no significant difference in the passage time of small intestine through capsule endoscopy between two groups（ P = 0. 57）. CONCLUSIONS: Simethicone can reduce the amount of bubbles in the intestinal tract and may improve the cleaning of intestinal tract

yet it does not increase the passage time of small intestine through the capsule endoscopy.

关键词

西甲硅油聚乙二醇电解质胶囊内镜Meta分析

Keywords

SimethiconePolyethylene glycol electrolyte powderCapsule endoscopyMeta-analysis

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Systematic Review of Huisheng Oral Liquid on Coagulation Function, Efficacy and Safety of Patients with Non-Small Cell Lung Cancer

Systematic Review of Efficacy and Safety of Dantian Jiangzhi Pills Combined with Statins in the Treatment of Hyperlipidemia

Systematic Review of Clinical Efficacy and Safety of Formula Granules of Liangfu Pill in the Treatment of Epigastric Pain

Systematic Review of Runzao Zhiyang Capsules Combined with Antihistamine in the Treatment of Chronic Urticaria

Meta-Analysis of Efficacy and Safety of Ticagrelor Combined with Rosuvastatin Therapy in the Treatment of Unstable Angina Pectoris

Related Author

ZHANG Jinhua

TIAN Yuan

YANG Xiaoping

ZHANG Yi

LIU Wei

LI Xingxing

FAN Zongjing

CUI Jie

Related Institution

Dept. of Oncology, Jingmen First People’s Hospital

Traditional Chinese Medicine Phenomics Research Center, Traditional Chinese Medicine Hospital Affiliated to Southwest Medical University

Dept. of Internal Medicine of Traditional Chinese Medicine, Shanghai Seventh People’s Hospital

Dept. of Internal Medicine of Traditional Chinese Medicine, Shanghai Tongren Hospital

Second School of Clinical Medicine, Beijing University of Chinese Medicine

⁰