OBJECTIVE: To probe into the clinical efficacy of low-dose colchicine and indomethacin combined with traditional Chinese medicine prescription in the treatment of arthritis gout rheumatism. METHODS: Totally 120 patients with arthritis gout rheumatism admitted into the outpatient department of Guilin Rehabilitation and Sanatorium Center of PLA from Oct. 2018 to Sept. 2019 were extracted to be divided into the control group and the study group via the random number table

with 60 cases in each group. The study group was treated with low-dose colchicine and indomethacin combined with traditional Chinese medicine

while the control group received conventional dose of colchicine and indomethacin. The overall efficacy

hematuria indicators [serum uric acid（ UA）

serum C-reactive protein（ CRP） and urine specific gravity] and incidence of adverse drug reactions in two groups were compared.RESULTS: The total effective rate in the study group was 76. 7%（ 46/60）

higher than 51. 7%（ 31/60） in the control group

the difference was statistically significant（ χ

2

= 10. 00

P

<

0. 05）. After treatment

various hematuria indicators in two groups were improved

the recovery of UA

CRP and urine specific gravity in the study group was significantly better than those in the control group

with statistically significant difference（ P

<

0. 05）. There were no severe adverse drug reactions in both groups during the treatment. CONCLUSIONS: The efficacy of low-dose colchicine and indomethacin combined with traditional Chinese medicine prescription in the treatment of arthritis gout rheumatism is significant

which is worth further study.