DONG Sizhe, LU Jianxun, YI Weidong, et al. Pharmaceutical Evaluation of Clinical Application Characteristics of Antineoplastic Perfusion Therapy. [J]. 20(11):1402-1405(2020)
DONG Sizhe, LU Jianxun, YI Weidong, et al. Pharmaceutical Evaluation of Clinical Application Characteristics of Antineoplastic Perfusion Therapy. [J]. 20(11):1402-1405(2020) DOI: 10.14009/j.issn.1672-2124.2020.11.030.
Pharmaceutical Evaluation of Clinical Application Characteristics of Antineoplastic Perfusion Therapy
摘要
恶性积液严重影响患者的生活质量。肿瘤灌注治疗作为局部治疗手段
能提高腔内药物浓度
有效清除游离微小病灶。目前
临床用于灌注治疗的抗肿瘤药包括铂类药物、紫杉类药物和氟尿嘧啶在内的化疗药
抗血管生成药
生物免疫调节剂以及抗肿瘤中药注射剂等。本文从药师的角度
对常用肿瘤灌注治疗药物的特点、剂量和安全性进行评价
为临床肿瘤局部灌注治疗的药物选择提供参考。
Abstract
Malignant effusion seriously affects the quality of life of patients. Antineoplastic perfusion therapy can increase concentrations of the drug for longer periods and remove the small lesions in the chest and abdominal cavity. At present
the clinical drugs used for antineoplastic perfusion therapy are mainly chemotherapeutic agents such as platinum drugs
taxane and 5-fluorouracil
blood vessel formation inhibitor
bioimmunomodulators and antineoplastic traditional Chinese medicine injection. From the perspective of pharmacists
this article evaluates the characteristics
doses and safety of commonly used antineoplastic perfusion therapy drugs
and provides reference for clinical drug selection.