Analysis of Clinical Application and Management Mode of Antibiotics in A Grade Ⅲ,Level A Hospital in Ningxia

WANG Jiyun; WANG Dan; WU Wenli; LU Zhaogang; MA Jing; LI Guokai; CHEN Wen; JING Jing; ZHANG Yanjie

doi:10.14009/j.issn.1672-2124.2020.11.023

您当前的位置：

首页 >

文章列表页 >

Analysis of Clinical Application and Management Mode of Antibiotics in A Grade Ⅲ,Level A Hospital in Ningxia

更新时间：2022-10-08

- Analysis of Clinical Application and Management Mode of Antibiotics in A Grade Ⅲ,Level A Hospital in Ningxia
- Vol. 20, Issue 11, Pages: 1374-1377(2020)
- 作者机构：
  
  1. 宁夏回族自治区人民医院/西北民族大学第一附属医院药学部临床药学室
  2. 宁夏回族自治区第三人民医院临床药学室
  3. 宁夏回族自治区人民医院/西北民族大学第一附属医院信息中心
  4. 宁夏回族自治区人民医院/西北民族大学第一附属医院纪检监察室
  5. 宁夏回族自治区人民医院/西北民族大学第一附属医院改革办公室
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2020.11.023
  CLC： R95
- Published：2020，
扫描看全文
[1]王基云,王丹,吴文利,陆钊罡,马婧,李国凯,陈雯,景晶,张彦杰.某三级甲等医院抗菌药物临床应用分析及管理模式探讨[J].中国医院用药评价与分析,2020,20(11):1374-1377+1382.

WANG Jiyun, WANG Dan, WU Wenli, et al. Analysis of Clinical Application and Management Mode of Antibiotics in A Grade Ⅲ,Level A Hospital in Ningxia. [J]. 20(11):1374-1377(2020)
[1]王基云,王丹,吴文利,陆钊罡,马婧,李国凯,陈雯,景晶,张彦杰.某三级甲等医院抗菌药物临床应用分析及管理模式探讨[J].中国医院用药评价与分析,2020,20(11):1374-1377+1382. DOI： 10.14009/j.issn.1672-2124.2020.11.023.

WANG Jiyun, WANG Dan, WU Wenli, et al. Analysis of Clinical Application and Management Mode of Antibiotics in A Grade Ⅲ,Level A Hospital in Ningxia. [J]. 20(11):1374-1377(2020) DOI： 10.14009/j.issn.1672-2124.2020.11.023.

摘要

目的:探讨宁夏回族自治区人民医院（以下简称"我院"）借助信息化系统开展抗菌药物临床应用管理模式。方法:将2017—2019年我院门急诊及住院病房抗菌药物临床应用情况作为研究对象

进行回顾性分析

包括临床使用率、用药频度（defined daily dose system

DDDs）、销售金额、微生物送检率及合理用药点评情况

综合评价管理模式。结果:与2017年比较

2018年、2019年我院门诊、急诊和住院患者抗菌药物使用率明显降低

门诊、急诊患者静脉输液使用率明显降低

住院患者Ⅰ类切口手术抗菌药物预防性使用率明显降低

住院患者抗菌药物单一使用率明显升高、联合用药率明显降低

住院患者非限制使用级抗菌药物使用率明显升高、限制使用级抗菌药物使用率明显降低

且2019年上述指标明显优于2018年

差异均有统计学意义（P <0.01）。与2017年比较

2018年、2019年门诊、住院患者抗菌药物销售金额占药品总销售金额的比例明显降低

住院患者非限制使用级抗菌药物销售金额占药品总销售金额的比例明显升高、限制使用级及特殊使用级抗菌药物销售金额占药品总销售金额的比例明显降低

差异均有统计学意义（P <0.05或P <0.01）。与2017年比较

微生物送检率明显升高

且2019年明显高于2018年

差异均有统计学意义（P <0.01）。与2017年比较

门急诊处方点评及住院医嘱点评中不合理处方/医嘱所占比例明显降低

差异均有统计学意义（P <0.05或P <0.01）。3年来

抗菌药物的DDDs发生变化。结论:通过大数据建立抗菌药物管理客观评价体系

使医院抗菌药物临床应用更合理

对医院抗菌药物临床应用管理具有指导意义。

Abstract

OBJECTIVE: To probe into the management mode of clinical application of antibiotics in People’s Hospital of Ningxia Hui Autonomous Region（ hereinafter referred to as "our hospital"） with the help of informationbased system. METHODS: The clinical application of antibiotics in outpatient and emergency department and inpatient wards of our hospital from 2017 to 2019 were selected as the research object. Retrospective analysis was conducted on clinical application rate

defined daily dose system（ DDDs）

consumption sum

microbiological test rate and review of rational drug application. And the management mode was comprehensively assessed. RESULTS: Compared with 2017

in 2018 and 2019

the application rate of antibiotics in outpatient

emergency and inpatient department in our hospital decreased significantly

the application rate of intravenous infusion in outpatient and emergency department decreased significantly

the preventive application rate of antibiotics in inpatients with type I incision surgery decreased significantly

the single application rate of antibiotics in inpatients decreased significantly and the combined application rate decreased significantly

the application rate of non-restricted-use antibiotics in inpatients increased significantly

and the application rate of restricted-use antibiotics decreased significantly

moreover

the above indicators in 2019 were significantly better than those in 2018

and the differences were statistically significant（ P < 0. 01）. Compared with 2017

in 2018 and 2019

the proportion of the consumption sum of antibiotics for outpatients and inpatients to the total consumption sum of drugs decreased significantly

the proportion of the consumption sum of non-restricted-use antibiotics to the total consumption sum of drugs increased significantly

the proportion of the consumption sum of restricted-use and special-use antibiotics in the consumption sum of drugs decreased significantly

the differences were statistically significant（ P < 0. 05 or P < 0. 01）. Compared with 2017

the microbiological test rate increased significantly

and the microbiological test rate in 2019 was significantly higher than that in 2018

with statistically significant differences（ P < 0. 01）. Compared with 2017

the proportion of irrational prescriptions/medical orders in outpatient and emergency prescription review and inpatient medical order review decreased significantly

and the difference was statistically significant（ P < 0. 05 or P < 0. 01）. Over the past 3 years

the DDDs of antibiotics changed.CONCLUSIONS: The establishment of objective evaluation system for antibiotics management through big data makes the clinical application of antibiotics more rational and has guiding significance for the clinical application and management of antibiotics in the hospital.

关键词

抗菌药物管理临床使用销售金额微生物送检合理用药

Keywords

AntibioticsManagementClinical applicationConsumption sumMicrobiological testRational drug application

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Investigation and Analysis of Perioperative Prophylactic Application of Antibiotics in 15 389Cases of Type Ⅰ Incision and Vascular Intervention Surgery

Application of 2018 Edition of National Essential Drugs Catalogue in Peking University Hospital of Stomatology

Effects of Involvement of Clinical Pharmacists in Standardized Antibiotics Management in Urinary Surgery Department

Effects of PDCA Cycles on Implementation of Antimicrobial Stewardship Program Led by Clinical Pharmacists

Investigation on Medication Status in Patients with Systemic Lupus Erythematosus in 109 Medical Institutions from 9 Cities in China from 2016 to 2020

Related Author

WANG Jiyun

WANG Dan

ZHANG Yanjie

LU Zhaogang

MA Jing

WANG Nan

JING Jing

WU Wenli

Related Institution

Dept. of Information Center, People ’s Hospital of Ningxia Hui Autonomous Region/the First Affiliated Hospital of Northwest Minzu University

Dept. of Medical Service,People’s Hospital of Ningxia Hui Autonomous Region/the First Affiliated Hospital of Northwest Minzu University

Dept.of Pharmacy,Peking University School of Stomatology/Peking University Hospital of Stomatology

Dept.of Clinical Pharmacy,Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University

Beijing Key Laboratory of Bio-characteristic Profiling for Evaluation of Rational Drug Use

⁰