Retrospective Analysis of Clinical Characteristics and Whole Process of Integrated Traditional Chinese and Western Medicine Treatment for 20 Patients with COVID-19

doi:10.14009/j.issn.1672-2124.2020.09.002

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Retrospective Analysis of Clinical Characteristics and Whole Process of Integrated Traditional Chinese and Western Medicine Treatment for 20 Patients with COVID-19

更新时间：2022-10-08

- Retrospective Analysis of Clinical Characteristics and Whole Process of Integrated Traditional Chinese and Western Medicine Treatment for 20 Patients with COVID-19
- Vol. 20, Issue 9, Pages: 1030-1037(2020)
- 作者机构：
  
  1. 武汉市第三医院(武汉大学附属同仁医院)药学部
  2. 中日友好医院药学部
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2020.09.002
  CLC： R563.1
- Published：2020，
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[1]陈灵,柳芳,夏杨,宋红艳,夏敬胜,卢江,陈永刚.20例新型冠状病毒肺炎患者临床特点及中西医结合治疗全过程的回顾性分析[J].中国医院用药评价与分析,2020,20(09):1030-1037.

Retrospective Analysis of Clinical Characteristics and Whole Process of Integrated Traditional Chinese and Western Medicine Treatment for 20 Patients with COVID-19. [J]. 20(9):1030-1037(2020)
[1]陈灵,柳芳,夏杨,宋红艳,夏敬胜,卢江,陈永刚.20例新型冠状病毒肺炎患者临床特点及中西医结合治疗全过程的回顾性分析[J].中国医院用药评价与分析,2020,20(09):1030-1037. DOI： 10.14009/j.issn.1672-2124.2020.09.002.

Retrospective Analysis of Clinical Characteristics and Whole Process of Integrated Traditional Chinese and Western Medicine Treatment for 20 Patients with COVID-19. [J]. 20(9):1030-1037(2020) DOI： 10.14009/j.issn.1672-2124.2020.09.002.

摘要

目的:探讨新型冠状病毒肺炎（COVID-19）患者的临床特点

并总结中西医结合治疗全过程及患者病情的发展与转归。方法:利用东华医院信息管理系统和美康临床药学管理系统

选取2020年1月25日至3月5日武汉市第三医院确诊为普通型COVID-19的20例患者作为研究对象

进行回顾性分析。20例患者从确诊入院起均接受抗病毒治疗

包括前5 d连续口服奥司他韦、后5～10 d连续口服阿比多尔

同时连续口服连花清瘟颗粒5～10 d;另外

所有患者均接受3～6 d莫西沙星治疗以及其他必须的支持护理（根据病情监测给予吸氧、营养支持治疗）。结果:经过中西医结合治疗后

20例患者的病毒性肺炎相关临床症状均消失

白细胞计数、中性粒细胞百分比和淋巴细胞百分比均恢复正常

胸部CT检查结果显示感染灶明显吸收。所有患者均经3次病毒核酸检测

结果均为阴性并出院。结论:本研究结果为COVID-19的治疗提供了线索

而奥司他韦、阿比多尔、连花清瘟颗粒联合莫西沙星等药物的疗效、安全性和合理性评价需要在未来的研究中进一步验证。

Abstract

OBJECTIVE: To probe into the clinical characteristics of patients with COVID-19

and to summarize the whole process of integrated traditional Chinese and Western medicine treatment and the development and outcome of the patients’ condition. METHODS: The information management system of Donghua Hospital and Meikang clinical pharmacy management system were used

20 patients diagnosed with common COVID-19 in Wuhan Third Hospital from Jan. 25th to Mar. 5th

2020 were selected as the research objects for retrospective analysis. Twenty patients received antiviral treatment from the time of diagnosis

including continuous oral administration of oseltamivir for 5 d

continuous oral administration of abidol for 5 to 10 d

and continuous oral administration of Lianhua Qingwen granules for 5 to 10 d.In addition

all patients received moxifloxacin treatment and other necessary supportive care （oxygen inhalation and nutritional support were given according to patients’ condition） for 3 to 6 d. RESULTS: After treatment of integrated traditional Chinese and Western medicine

all clinical symptoms related to COVID-19 of 20 patients disappeared

white blood cell count

neutrophil percentage and lymphocyte percentage all returned to the normal levels

and chest CT examination results showed that the infection lesions were obviously absorbed. All patients were tested three times for viral nucleic acids

which were negative and discharged from the hospital. CONCLUSIONS: The results of this study provide clues for the treatment of COVID-19

and the efficacy

safety and rationality of oseltamivir

abidor

Lianhua Qingwen granules combined with moxixacin are supposed to be further verified in future studies.

关键词

新型冠状病毒肺炎阿比多尔奥司他韦莫西沙星连花清瘟颗粒

Keywords

COVID-19ArbidolOseltamivirMoxifloxacinLianhua Qingwen granules

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