OBJECTIVE:To compare the efficacy and prognosis of goserelin acetate sustained-release implants and drospirenone ethinylestradiol tablets（Ⅱ） assisted endometrial polyp resection in the treatment of endometrial polyps.METHODS:Retrospective analysis was conducted on 95 patients with endometrial polyps admitted into Huangshi Maternal and Child Healthcare Hospital of Hubei Edong Medical Group from Jun.2017 to May 2018.According to different treatment methods

all patients were divided into the control group（drospirenone ethinylestradiol tablets（Ⅱ）assisted endometrial polyp resection treatment

n = 47） and the observation group（goserelin acetate sustained-release implants and drospirenone ethinylestradiol tablets（Ⅱ） assisted endometrial polyp resection treatment

n = 48）.The clinical efficacy

recurrence of endometrial polyp

endometrial thickness

menstruation

sex hormone levels [follicle stimulating hormone（FSH）

estradiol（E

2

） and luteinizing hormone（LH） ]and safety were compared between two groups.RESULTS:The total effective rate was 89.58%（43/48） in the observation group

slightly higher than80.85%（38/47） in the control group;the recurrence rate of endometrial polyp at 6-month follow-up in the observation group was 6.25%（3/48）

slightly lower than that in the control group 17.02%（8/47）

difference was not statistically significant（P

>

0.05）.After 3 and 6 months of treatment

endometrial thickness

menstruation

FSH

E

2

and LH levels of both groups decreased significantly

and the observation group was significantly lower than the control group

with statistically significant differences（P

<

0.05）.During the treatment process

the incidence of adverse drug reactions in the observation group was 18.75%（9/48）

significantly lower than that in the control group38.30%（18/47）

and the difference was statistically significant（P

<

0.05）.CONCLUSIONS:Goserelin acetate sustained-release implants was more effective than drospirenone ethinylestradiol tablets（Ⅱ） in the adjuvant treatment of patients with endometrial polyps undergoing electrosurgical resection

which can obviously improve the clinical symptoms of patients

regulate the levels of sex hormones with higher safety

and is beneficial to improve the prognosis of patients.