OBJECTIVE:To compare conception control and safety among Drospirenone ethinyl estradiol tablets（Ⅱ）

etonogestrel implants and levonorgestrel intrauterine contraceptive system after negative pressure suction for artificial abortion.METHODS:223 healthy women with unintended pregnancy undergoing negative pressure suction for artificial abortion admitted into Wuxi Maternal and Child Health Hospital Affiliated to Nanjing Medical University from Jan.2018 to Jul.2019 were retrospectively analyzed.The 223 patients were divided into group A（treated with Drospirenone ethinyl estradiol tablets（Ⅱ） orally

68 cases）

group B（given etonogestrel implants for hypodermic implantation

75 cases） and group C（treated with levonorgestrel intrauterine contraceptive system

80 cases） according to different postoperative contraceptive methods.The vaginal bleeding time

menstrual recovery time and uterine recovery after abortion

the re-unplanned pregnancy rate

removal rate of contraceptive measures and continued use rate within 6 months after operation of the three groups were observed

differences in incidences of bleeding and menstruation of the three groups were compared.RESULTS:Compared with group A

the vaginal bleeding time and menstrual recovery time of group B and group C were significantly shorter

and the endometrial thickness was significantly thinner

with statistically significant differences（P < 0.05）

while there were no statistical significance in differences in the above indicators between group B and group C（P>0.05）.Compared with group C

the re-unplanned pregnancy rates with 6 months after operation of group A and group B were significantly lower

and the continued use rate was significantly higher

with statistically significant differences（P<0.05）;while there were no statistical significance in differences in re-unplanned pregnancy rate

removal rate of contraceptive measures and continued use rate within 6 months after operation between group B and group C（P > 0.05）.The incidences of bleeding

spanomenorrhea and amenorrhea of group B and group C were significantly higher than those of group A;the incidence of amenorrhea of group B was significantly higher than that of group C;the incidence of menostaxis of group C was significantly higher than that of group A

with statistically significant differences（P < 0.05）.CONCLUSIONS:Drospirenone ethinyl estradiol tablets（Ⅱ）

etonogestrel implants and levonorgestrel intrauterine contraceptive system can all achieve better conception control.Drospirenone ethinyl estradiol tablets（Ⅱ） has less effect on endometrium and menstrual patterns

while etonogestrel implants and levonorgestrel intrauterine contraceptive system have more advantages in long-term contraceptive management

but the patients should be selected reasonably to minimize the occurrence of breakthrough bleeding.