Analysis of Application of Glaucoma Treatment Drugs in 114 Grade Ⅲ Level A hospitals in China from 2015 to 2017

YANG Jiali; LIU Xuemei; CHEN Yue; ZHANG Haiying; HUANG Lin; FENG Yufei; BIAN Jiaming

doi:10.14009/j.issn.1672-2124.2020.07.021

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Analysis of Application of Glaucoma Treatment Drugs in 114 Grade Ⅲ Level A hospitals in China from 2015 to 2017

更新时间：2022-10-08

- Analysis of Application of Glaucoma Treatment Drugs in 114 Grade Ⅲ Level A hospitals in China from 2015 to 2017
- Vol. 20, Issue 7, Pages: 850-853(2020)
- 作者机构：
  
  1. 北京大学人民医院药剂科
  2. 中国人民解放军总医院第七医学中心药理科
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2020.07.021
  CLC： R988.1
- Published：2020，
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[1]杨佳丽,刘雪梅,陈月,张海英,黄琳,封宇飞,边佳明.2015—2017年全国114家三级甲等医院青光眼治疗药物应用现状分析[J].中国医院用药评价与分析,2020,20(07):850-853+858.

YANG Jiali, LIU Xuemei, CHEN Yue, et al. Analysis of Application of Glaucoma Treatment Drugs in 114 Grade Ⅲ Level A hospitals in China from 2015 to 2017. [J]. 20(7):850-853(2020)
[1]杨佳丽,刘雪梅,陈月,张海英,黄琳,封宇飞,边佳明.2015—2017年全国114家三级甲等医院青光眼治疗药物应用现状分析[J].中国医院用药评价与分析,2020,20(07):850-853+858. DOI： 10.14009/j.issn.1672-2124.2020.07.021.

YANG Jiali, LIU Xuemei, CHEN Yue, et al. Analysis of Application of Glaucoma Treatment Drugs in 114 Grade Ⅲ Level A hospitals in China from 2015 to 2017. [J]. 20(7):850-853(2020) DOI： 10.14009/j.issn.1672-2124.2020.07.021.

摘要

目的:了解2015—2017年全国114家三级甲等医院青光眼治疗药物应用现状

旨在探讨我国青光眼药物治疗的发展趋势

同时为临床合理用药提供参考。方法:抽取114家医院门诊眼科和五官科诊断为青光眼或高眼压症患者的用药数据

对青光眼治疗药物应用情况、用药频度（defined daily dose system

DDDs）、限定日费用（defined daily cost

DDC）、年增长率以及青光眼禁忌慎用药物等进行分析评价。结果:中成药及β肾上腺素能受体拮抗剂使用量最大

临床信任度高;各类药物的DDDs及DDC相对稳定但有波动

其中复方制剂滴眼液的DDDs呈现逐年缓慢增加的趋势

而其DDC呈现逐年缓慢降低的趋势。真实世界中

青光眼患者存在使用青光眼禁忌慎用药物的情况。结论:临床青光眼治疗药物总体使用情况合理

但青光眼患者存在使用青光眼禁忌慎用药物的情况

还需进一步优化。

Abstract

OBJECTIVE: To investigate the application status of glaucoma treatment drugs in 114 grade Ⅲ level A hospitals in China from 2015 to 2017

and to explore the development trend of glaucoma drug therapy in China

so as to provide reference for clinical rational drug use.METHODS: Medication data of patients diagnosed with glaucoma or ocular hypertension in outpatient ophthalmology and department of ENT in 114 hospitals were extracted to analyze and evaluate the application of glaucoma drugs

defined daily dose system（ DDDs）

defined daily cost（ DDC）

annual growth rate and drugs contraindicated for glaucoma.RESULTS: The consumption amount of traditional Chinese medicines and β-adrenergic receptor antagonists took the lead

with high levels of clinical confidence.The DDDs and DDC of various drugs were relatively stable but fluctuated

among which the DDDs of compound drug eye drops showed the trend of slow increase year by year

while the DDC showed the trend of slow decrease year by year.In the real world

there were cases of glaucoma patients using drugs that were contraindicated for glaucoma.CONCLUSIONS: The overall use of clinical glaucoma drugs is rationale

yet it is necessary to further optimize the use of drugs contraindicated for glaucoma in patients with glaucoma.

关键词

青光眼治疗药物销售金额用药频度现状分析

Keywords

Glaucoma treatment drugsConsumption sumDefined daily dose systemStatus analysis

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