Effects and Pharmaceutical Care of Antiviral Drugs in the Treatment of COVID-19 on Blood Glucose and Antidiabetic Drugs

RAN Yajuan; QIU Sha; QIAN Yan

doi:10.14009/j.issn.1672-2124.2020.05.003

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Effects and Pharmaceutical Care of Antiviral Drugs in the Treatment of COVID-19 on Blood Glucose and Antidiabetic Drugs

更新时间：2022-10-08

- Effects and Pharmaceutical Care of Antiviral Drugs in the Treatment of COVID-19 on Blood Glucose and Antidiabetic Drugs
- Vol. 20, Issue 5, Pages: 521-525(2020)
- 作者机构：
  
  重庆医科大学附属第二医院药学部
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2020.05.003
  CLC： R969;R563.1
- Published：2020，
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[1]冉娅娟,邱莎,钱妍.新型冠状病毒肺炎治疗中抗病毒药对血糖和抗糖尿病药的影响及药学监护[J].中国医院用药评价与分析,2020,20(05):521-525.

RAN Yajuan, QIU Sha, QIAN Yan. Effects and Pharmaceutical Care of Antiviral Drugs in the Treatment of COVID-19 on Blood Glucose and Antidiabetic Drugs. [J]. 20(5):521-525(2020)
[1]冉娅娟,邱莎,钱妍.新型冠状病毒肺炎治疗中抗病毒药对血糖和抗糖尿病药的影响及药学监护[J].中国医院用药评价与分析,2020,20(05):521-525. DOI： 10.14009/j.issn.1672-2124.2020.05.003.

RAN Yajuan, QIU Sha, QIAN Yan. Effects and Pharmaceutical Care of Antiviral Drugs in the Treatment of COVID-19 on Blood Glucose and Antidiabetic Drugs. [J]. 20(5):521-525(2020) DOI： 10.14009/j.issn.1672-2124.2020.05.003.

摘要

新型冠状病毒肺炎（COVID-19）是指由严重急性呼吸综合征冠状病毒2型（severe acute respiratory syndrome coronavirus 2

SARS-CoV-2）感染引起的传染性疾病。针对此次病毒感染

国家卫生健康委员会已更新诊疗方案至《新型冠状病毒肺炎诊疗方案（试行第七版）》

推荐的抗病毒药有α干扰素、洛匹那韦/利托那韦、利巴韦林、阿比多尔和磷酸氯喹。为进一步保障上述药物在临床的安全使用

本文通过查阅相关文献

结合药动学特点和循证证据

探讨方案中抗病毒药对血糖的影响以及与抗糖尿病药的相互作用

提出药学监护建议。

Abstract

COVID-19 is a kind of infectious disease induced by severe acute respiratory syndrome coronavirus 2（SARS-CoV-2） infection. In response to the infection

the National Health Commission of the People’s Republic of China issued the Diagnostic and Therapeutic Protocol of COVID-19（Trial Seventh Edition）

antiviral drugs including interferon-α

lopinavir/ritonavir

ribavirin

abidol and chloroquine phosphate were recommended. In order to further ensure the safe use of the above drugs in clinical practice

this paper discusses the effects of antiviral drugs on blood glucose and the interaction with antidiabetic drugs in the regimen by referring to relevant literature

and formulates suggestions on pharmaceutical care combined with the pharmacokinetic characteristics and evidence-based evidence.

关键词

新型冠状病毒肺炎抗病毒药血糖药物相互作用药学监护

Keywords

COVID-19Antiviral drugsBlood glucoseDrug interactionPharmaceutical care

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