OBJECTIVE: To explore the countermeasures of supervision of adjuvant drugs in medical institutions

so as to promote the rational drug use. METHODS: The catalogue of adjuvant drugs was determined by defining the definition of adjuvant drugs and formulating the criteria for the definition of adjuvant drugs. Countermeasures such as prescription review

dynamic monitoring

hierarchical management

propaganda and training of rational drug use were adopted to strengthen the supervision of adjuvant drug use. The data of adjuvant drug use before supervision（ 2017）and after supervision（ 2018） were collected from the information department of Chongming Branch

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine（ hereinafter referred to as "our hospital"）. SPSS 19. 0 statistical software was used to compare and analyze the data of drug proportion

average outpatient drug cost and average inpatient drug cost per patient. RESULTS: Our hospital had made remarkable achievements in the supervision of adjuvant drugs. The drug proportion before and after supervision was about 45% and 32%

respectively. The average outpatient drug cost was about 260 yuan and 190 yuan

respectively. And the average inpatient drug cost was about4 000 yuan and 3 000 yuan

respectively. The indicators after supervision were significantly better than those before supervision

and the differences were statistically significant（ P < 0. 05）. The clinical irrational use of adjuvant drugs was also significantly improved. CONCLUSIONS: Strengthening the supervision of adjuvant drug use can not only reduce drug expenses and the burden of patients

but also promote the rational drug use. However

due to the lack of policy support

there are still many confusions in the supervision of adjuvant drugs

and it is urgent for the national health authorities to introduce adjuvant drug management policies.