Analysis on the Application of Antipsychotic Drugs in 1 743 Inpatients with Mental Disorders

ZHUANG Hongyan; LIU Shanshan; GUO Wei; BAO Shuang

doi:10.14009/j.issn.1672-2124.2020.02.028

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Analysis on the Application of Antipsychotic Drugs in 1 743 Inpatients with Mental Disorders

更新时间：2022-10-08

- Analysis on the Application of Antipsychotic Drugs in 1 743 Inpatients with Mental Disorders
- Vol. 20, Issue 2, Pages: 232-234(2020)
- 作者机构：
  
  1. 首都医科大学附属北京安定医院药事部国家精神心理疾病临床医学研究中心精神疾病诊断与治疗北京市重点实验室
  2. 首都医科大学人脑保护高精尖创新中心
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2020.02.028
  CLC： R95
- Published：2020，
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[1]庄红艳,刘珊珊,果伟,鲍爽.1743例住院精神疾病患者抗精神病药应用分析[J].中国医院用药评价与分析,2020,20(02):232-234+238.

ZHUANG Hongyan, LIU Shanshan, GUO Wei, et al. Analysis on the Application of Antipsychotic Drugs in 1 743 Inpatients with Mental Disorders. [J]. 20(2):232-234(2020)
[1]庄红艳,刘珊珊,果伟,鲍爽.1743例住院精神疾病患者抗精神病药应用分析[J].中国医院用药评价与分析,2020,20(02):232-234+238. DOI： 10.14009/j.issn.1672-2124.2020.02.028.

ZHUANG Hongyan, LIU Shanshan, GUO Wei, et al. Analysis on the Application of Antipsychotic Drugs in 1 743 Inpatients with Mental Disorders. [J]. 20(2):232-234(2020) DOI： 10.14009/j.issn.1672-2124.2020.02.028.

摘要

目的:了解首都医科大学附属北京安定医院（以下简称"我院"）住院精神疾病患者抗精神病药使用现状

为临床合理用药提供依据。方法:以2017年1月至2019年6月我院普通精神科住院精神疾病患者抗精神病药医嘱为依据

分析患者人口学资料、不同年龄段患者使用抗精神病药的种类分布、单一抗精神病药使用种类及频率、不同年龄和性别患者抗精神病药使用剂量等

探讨住院患者抗精神病药的使用特点。结果:共纳入1 743例住院精神疾病患者

使用频率排序居前5位的抗精神病药依次为利培酮、奥氮平、喹硫平、阿立哌唑和帕利哌酮;单一抗精神病药使用频率排序居前3位的药品依次为利培酮、奥氮平和喹硫平。青少年患者使用利培酮、奥氮平、喹硫平和帕利哌酮的剂量显著高于中老年患者;男性患者使用利培酮、奥氮平、喹硫平和阿立哌唑的剂量显著高于女性。结论:住院精神疾病患者使用的抗精神病药主要为非典型抗精神病药

以利培酮、喹硫平和奥氮平为主;不同年龄、不同性别患者抗精神病药的使用剂量不同。

Abstract

OBJECTIVE: To investigate the application of antipsychotic drugs in inpatients with mental disorders in Beijing Anding Hospital

Capital Medical University( hereinafter referred to as "our hospital "

so as to provide references for clinical rational medication. METHODS: Based on the medical orders of antipsychotic drugs for inpatients with mental disorders in the general psychiatric department of our hospital from Jan. 2017 to Jun. 2019

the demographics

distribution of categories of antipsychotic drugs used by patients at different ages

types and frequency of the application of single antipsychotic drugs

dosages of antipsychotic drugs for patients with different ages and genders were analyzed

so as to probe into the characteristics of antipsychotic drugs used in inpatients. RESULTS: A total of 1 743 inpatients with mental disorders were involved

the top 5 antipsychotic drugs ranked by frequency of application were respectively risperidone

olanzapine

quetiapine

aripiprazole and paliperidone; the top 3 single antipsychotic drugs ranked by frequency of application were respectively risperidone

olanzapine and quetiapine. The dosages of risperidone

olanzapine

quetiapine and paliperidone in adolescent patients were significantly higher than that in middle-aged and elderly patients; the dosage of risperidone

olanzapine

quetiapine and aripiprazole in male patients was significantly higher than that in female patients. CONCLUSIONS: The antipsychotic drugs applied in inpatients with mental disorders are mainly atypical antipsychotic drugs

including risperidone

quetiapine and olanzapine; the dosage of antipsychotic drugs differs from patients with different ages and genders.

关键词

抗精神病药精神疾病住院患者

Keywords

Antipsychotic drugsMental disordersInpatients

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