OBJECTIVE: To probe into the clinical effects of carboprost methylate suppository combined with hysteroscopy suction surgery system in treatment of induced abortion with early high-risk pregnancy. METHODS: 400 patients with early high-risk pregnancy and voluntary induced abortion admitted into the Sixth People’s Hospital of Nanning from Jan. 2018 to Jan. 2019 were enrolled and divided into control group and observation group via random number table

with 200 cases in each group. The control group was treated with hysteroscopy suction surgery system to terminate pregnancy

while the observation group was given carboprost methylate suppository before surgery based on the control group to terminate pregnancy. Differences in surgery-related indices

general satisfaction with cervical softening and incidences of complication were compared between two groups. RESULTS: The duration of surgery

amount of bleeding

duration of postoperative vaginal bleeding and amount of postoperative vaginal bleeding of observation group were significantly better than those of the control group

with statistically significant differences（ P<0. 05）; the general satisfaction with cervical softening of observation group was 97. 00%（ 194/200）

which was significantly higher than that of the control group（ 86. 00%

172/200）

with statistically significant difference（ P < 0. 05）; the incidence of complication of observation group was 1. 00%（ 2/200）

which was significantly lower than that of the control group（ 7. 00%

14/200）

with statistically significant difference（ P<0. 05）. CONCLUSIONS: For patients with early high-risk undergoing induced abortion

the combination of carboprost methylate suppository and hysteroscopy suction surgery system has a good effect

which can shorten the duration of surgery and vaginal bleeding

reduce the amount of intraoperative bleeding and vaginal bleeding

improve patient’s satisfaction with cervical softening

with few complications.