Efficacy of Compound Taizishen Granule Combined with Conventional Western Medicine in Treatment of Recurrent Respiratory Tract Infection in Children and its Effect on Immune Function

WEI Zhuang; LIANG Aimin; JI Wenjing

doi:10.14009/j.issn.1672-2124.2020.02.010

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Efficacy of Compound Taizishen Granule Combined with Conventional Western Medicine in Treatment of Recurrent Respiratory Tract Infection in Children and its Effect on Immune Function

更新时间：2022-10-08

- Efficacy of Compound Taizishen Granule Combined with Conventional Western Medicine in Treatment of Recurrent Respiratory Tract Infection in Children and its Effect on Immune Function
- Vol. 20, Issue 2, Pages: 169-170(2020)
- 作者机构：
  
  首都医科大学附属北京儿童医院保健中心
- 作者简介：
- 基金信息：
- DOI：10.14009/j.issn.1672-2124.2020.02.010
  CLC： R725.6
- Published：2020，
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[1]魏庄,梁爱民,纪文静.复方太子参颗粒联合西医常规治疗用于儿童反复呼吸道感染的疗效及对患儿免疫功能的影响[J].中国医院用药评价与分析,2020,20(02):169-170+175.

WEI Zhuang, LIANG Aimin, JI Wenjing. Efficacy of Compound Taizishen Granule Combined with Conventional Western Medicine in Treatment of Recurrent Respiratory Tract Infection in Children and its Effect on Immune Function. [J]. 20(2):169-170(2020)
[1]魏庄,梁爱民,纪文静.复方太子参颗粒联合西医常规治疗用于儿童反复呼吸道感染的疗效及对患儿免疫功能的影响[J].中国医院用药评价与分析,2020,20(02):169-170+175. DOI： 10.14009/j.issn.1672-2124.2020.02.010.

WEI Zhuang, LIANG Aimin, JI Wenjing. Efficacy of Compound Taizishen Granule Combined with Conventional Western Medicine in Treatment of Recurrent Respiratory Tract Infection in Children and its Effect on Immune Function. [J]. 20(2):169-170(2020) DOI： 10.14009/j.issn.1672-2124.2020.02.010.

摘要

目的:探讨复方太子参颗粒联合西医常规治疗用于儿童反复呼吸道感染的疗效及对患儿免疫功能的影响。方法:选取2017年1月至2018年12月首都医科大学附属北京儿童医院收治的3～10岁反复呼吸道感染患儿157例

采用随机数字表法分为治疗组79例和对照组78例。对照组患儿给予一般对症治疗（如退热、止咳及解除卡他症状等）和抗感染治疗

治疗组患儿在对照组的基础上给予复方太子参颗粒。观察两组患儿的临床疗效

比较两组患儿治疗前后免疫球蛋白G（Ig G）、免疫球蛋白A（Ig A）及免疫球蛋白M（Ig M）水平的差异。结果:治疗组患儿的总有效率为91. 14%（72/79）

明显高于对照组的73. 08%（57/78）

差异有统计学意义（P<0. 05）。治疗1个月后

治疗组患儿的Ig G、Ig A水平明显高于治疗前及对照组治疗后

差异均有统计学意义（P<0. 05）;但两组患儿Ig M水平的差异无统计学意义（P>0. 05）。结论:复方太子参颗粒联合西医常规治疗可降低儿童反复呼吸道感染的复发率

显著提高患儿的免疫功能。

Abstract

OBJECTIVE: To probe into the Efficacy of compound Taizishen granule combined with conventional western medicine in treatment of recurrent respiratory tract infection in children and its effect on immune function.METHODS: 157 children aged between 3-10 with recurrent respiratory tract infection admitted into Beijing Children’s Hospital Affiliated to Capital Medical University from Jan. 2017 to Dec. 2018 were selected and divided into treatment group（ 79 cases） and control group（ 78 cases） via random number table. The control group was given conventional symptomatic treatment（ including anti-febrile

antitussive and catarrh relieve） and anti-infective therapy

while the treatment group was given compound Taizishen granule based on the control group. The clinical efficacy of both groups was observed

differences in immune globulin G（ Ig G）

immune globulin A（ Ig A） and immune globulin M（ Ig M）levels between two groups before and after treatment were compared. RESULTS: The total effective rate of treatment group was 91. 14%（ 72/79）

which was significantly higher than that of the control group（ 73. 08%

57/78）

with statistically significant difference（ P<0. 05）. At 1 month after treatment

the Ig G and Ig A levels of treatment group were significantly higher than those of before treatment and the control group

with statistically significant differences（ P <0. 05）; while there was no statistical significance in the difference of Ig M levels between two groups（ P > 0. 05）.CONCLUSIONS: The combination of compound Taizishen granule and conventional western medicine can reduce the recurrence rate of recurrent respiratory tract infection in children

which can significantly improve children’s immunity.

关键词

复方太子参颗粒反复呼吸道感染儿童体液免疫

Keywords

Compound Taizishen granuleRecurrent respiratory tract infectionChildrenHumoral immunity

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