Motherwort injection is a kind of Chinese patent medicine preparation prepared by extracting effective substance from the motherwort herb of the labiatae family. The main component is the total alkaloid of motherwort

whose main function is to regulate menstruation and stop bleeding

and has the effect of contracting the uterus. This study systematically retrieved the databases of CNKI

Wanfang database

VIP database and PubMed to comb the literature on the clinical drug combination of motherwort injection

and then carried out the review and analysis. The results of the study showed that the carboprost methylate suppositorites was easy to be administered

and the combination with the motherwort injection was effective in contracting the uterus and uterine bleeding. The drug combination of misoprostol and motherwort injection had synergistic effect

which made the uterine contraction time longer

and the effect of rectal administration of misoprostol on the prevention of postpartum hemorrhage was significant. Carboprost methylate suppositories combined with motherwort injection was not suitable for postpartum hemorrhage in patients with pregnancy-induced hypertension. Oxytocin injection combined with motherwort injection can be used to prevent postpartum hemorrhage during cesarean section of pregnancy-induced hypertension

but the half-life of oxytocin injection was short. And the drug dose was not completely positively related to the effect of promoting uterine contraction. Carboprost trometamine injection had a long half-life

and carboprost trometamine injection combined with motherwort injection can shorten the duration of the third stage of labor and improve coagulation function. Motherwort injection combined with the above four drugs had significant effect on the prevention and treatment of postpartum hemorrhage. In clinical application

it is necessary to comprehensively consider whether perinatal women have other syndromes

the characteristics of the drug’s effects and adverse reactions

so that the clinical combined use of motherwort injection can achieve better efficacy. In clinical application

it is necessary to comprehensively consider whether perinatal women have other syndromes

the characteristics of the drug’s effects and adverse drug reactions

so that the clinical drug combination of motherwort injection can achieve better efficacy. It is hoped that this study can provide reference for the application and further research of clinical drug combination of motherwort injection.