Dopamine Combined with Captopril in the Treatment of Children with Pneumonia Complicated with Heart Failure

Wei Wei; Huang Airong

doi:10.13407/j.cnki.jpp.1672.108X.2021.08.007

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Dopamine Combined with Captopril in the Treatment of Children with Pneumonia Complicated with Heart Failure

更新时间：2022-11-03

- Dopamine Combined with Captopril in the Treatment of Children with Pneumonia Complicated with Heart Failure
- Vol. 27, Issue 8, Pages: 25-28(2021)
- 作者机构：
  
  1. 湖北省随州市中心医院,湖北,随州,441300
  2. 随州市中医医院,湖北,随州,441300
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672.108X.2021.08.007
  CLC：
- Published：2021，
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Wei Wei, Huang Airong. Dopamine Combined with Captopril in the Treatment of Children with Pneumonia Complicated with Heart Failure. [J]. 27(8):25-28(2021)
DOI：

Wei Wei, Huang Airong. Dopamine Combined with Captopril in the Treatment of Children with Pneumonia Complicated with Heart Failure. [J]. 27(8):25-28(2021) DOI： 10.13407/j.cnki.jpp.1672.108X.2021.08.007.

摘要

目的：探讨多巴胺联合卡托普利在肺炎合并心力衰竭患儿中的应用价值。方法：选取2016-2018年湖北省随州市中心医院住院治疗的肺炎合并心力衰竭患儿92例，按随机数表法分为对照组和研究组各46例。对照组患儿给予常规治疗，研究组患儿给予多巴胺联合卡托普利治疗，观察两组患儿临床症状体征、心肌酶水平改善情况，评价疗效及用药安全性。结果：与对照组相比，研究组治疗后心率（HR）、呼吸频率（RR）、乳酸脱氢酶（LDH）、天门冬氨酸氨基转移酶（AST）、肌酸激酶（CK）、肌酸激酶同工酶（CK-MB）均降低，而血氧饱和度（SaO2）升高；研究组住院时间、HR及RR恢复正常时间、听诊肺部啰音及喘促消失时间均短于对照组（P均<0.05）。两组患儿不良反应发生率比较差异无统计学意义。结论：多巴胺联合卡托普利可显著缓解小儿肺炎合并心力衰竭的临床症状体征，改善心肌酶水平，缩短住院时间，且用药安全性较高。

Abstract

Objective: To probe into the application value of dopamine combined with captopril in the treatment of children with pneumonia complicated with heart failure. Methods: A total of 92 children with pneumonia complicated with heart failure admitted into Hubei Suizhou Central Hospital from 2016 to 2018 were extracted to be divided into the control group and the study group via the random number table

with 46 cases in each group. The control group was given conventional treatment

while the study group received dopamine combined with captopril. The clinical symptoms and signs

the improvement of myocardial enzyme levels in two groups were observed

and the clinical efficacy and drug safety were evaluated. Results: Compared with the control group

the heart rate (HR)

respiratory rate (RR)

lactate dehydrogenase (LDH)

aspartate transaminase (AST)

creatine kinase (CK) and creatine kinase isoenzyme (CK-MB) decreased in the study group after treatment

while the blood oxygen saturation (SaO2) increased. The length of stay

the recovery time of HR and RR

the disappearance time of lung rales and wheezing in the study group were shorter than those in the control group (P<0.05). There was no statistically significant difference in the incidence of adverse drug reactions between two groups. Conclusion: Dopamine combined with captopril can significantly alleviate the clinical symptoms and signs of children with pneumonia complicated with heart failure

improve the myocardial enzyme levels and shorten the length of stay with higher safety.

关键词

儿童肺炎合并心力衰竭多巴胺卡托普利临床结局

Keywords

childrenpneumonia complicated with heart failureopaminecaptoprilclinical outcome

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