Clinical Characteristics and Risk Factors of Necrotizing Enterocolitis in Term Infants and Preterm Infants

Liu Jing; Yu Jialin

doi:10.13407/j.cnki.jpp.1672.108X.2021.03.004

您当前的位置：

首页 >

文章列表页 >

Clinical Characteristics and Risk Factors of Necrotizing Enterocolitis in Term Infants and Preterm Infants

更新时间：2022-11-03

- Clinical Characteristics and Risk Factors of Necrotizing Enterocolitis in Term Infants and Preterm Infants
- Vol. 27, Issue 3, Pages: 14-17(2021)
- 作者机构：
  
  重庆医科大学附属儿童医院，儿童发育疾病研究教育部重点实验室，儿童发育重大疾病国家国际科技合作基地，儿科学重庆市重点实验室,重庆,400014
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672.108X.2021.03.004
  CLC：
- Published：2021，
扫描看全文
Liu Jing, Yu Jialin. Clinical Characteristics and Risk Factors of Necrotizing Enterocolitis in Term Infants and Preterm Infants. [J]. 27(3):14-17(2021)
DOI：

Liu Jing, Yu Jialin. Clinical Characteristics and Risk Factors of Necrotizing Enterocolitis in Term Infants and Preterm Infants. [J]. 27(3):14-17(2021) DOI： 10.13407/j.cnki.jpp.1672.108X.2021.03.004.

摘要

目的：探讨早产儿与足月儿坏死性小肠结肠炎（NEC）的临床特征、危险因素及预后。方法：采用回顾性研究方法，收集2016-2018年在重庆医科大学附属儿童医院诊断为新生儿NEC的325例住院患儿的病历资料，根据胎龄分为足月儿与早产儿，分别从发病日龄、临床表现、主要合并症等方面分析。结果：足月儿组多表现为便血、呕吐（P<0.05），早产儿组多表现为腹胀、肠鸣音减弱等（P<0.05）；早产儿组NEC并发症发生率明显高于足月儿组（P<0.05）；与足月儿组比较，早产儿组明显预后不良（P<0.01）。新生儿败血症、休克、先天性心脏病3个变量是影响NEC临床结局的独立危险因素（P<0.05）。结论：注意防治各胎龄段新生儿高危因素，密切观察临床表现，辅助检查，预防及减少并发症等有助于减少NEC的发生及改善预后。

Abstract

Objective: To probe into the clinical features

risk factors and prognosis of necrotizing enterocolitis (NEC) in preterm infants and term infants. Methods: Totally 325 neonates diagnosed with NEC in the Children’s Hospital of Chongqing Medical University from 2016 to 2018 were retrospectively analyzed with the clinical data

clinical manifestations and major complications

and all children were divided into the term infant group and preterm infant group according to the gestational age. Results: Blood stool and vomiting were the most common clinical manifestations of the term infants (P<0.05)

abdominal distension and hypoactive bowel sounds were the most common clinical manifestations of the preterm infants (P<0.05). The incidence of NEC complications in the preterm infant group was significantly higher than that in the term infant group (P<0.05). There was statistically significant difference between the term infant group and the the preterm infant group in poor prognosis (P<0.01). Neonatal sepsis

neonatal shock and congenital heart disease were independent risk factors affecting the clinical outcome of NEC (P<0.05). Conclusion: Paying attention to the prevention and treatment of high risk factors of all gestational age groups of neonates

closely observing clinical manifestations

auxiliary examination

prevention and reduction of complications are helpful to reduce the incidence of NEC and improve the prognosis.

关键词

早产儿足月儿坏死性小肠结肠炎危险因素

Keywords

preterm infantsterm infantsnecrotizing enterocolitisrisk factos

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Transfusion-associated Necrotizing Enterocolitis in Very Low Birth Weight Infants: Meta-Analysis ofObservational Data

Pharmaceutical Care for a Case of Extremely Low Birth Weight Preterm Infant with Metabolic Bone Disease by Clinical Pharmacists

Effects of Pulmonary Surfactant on Cerebral Oxygen Metabolism in Preterm Infants

Incidence and Outcome of Group B Streptococcus Infection in Premature Infants with Premature Rupture of Membranes

Application Value of Glucocorticoid in the Treatment of Early Bronchopulmonary Dysplasia

Related Author

Bu Jun

Liu Ye

Li Zhiping

Yang Lei

Zhu Lin

Ma Yunxia

Li Xufang

Zheng Wei

Related Institution

Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai

National Children’s Medical Center, Children’s Hospital of Fudan University

Children’s Hospital of Yuxi, Yunan Yuxi

Guangzhou Women and Children’s Medical Center

Shuyang Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Shuyang

⁰