To probe into the efficacy of drug therapy combined with behavioral intervention in the treatment of children with vitamin D deficiency

so as to provide reference for the treatment of vitamin D deficiency in clinic. Methods: A total of 610 children (from 3 months to 3 years old) who underwent the physical examination in our hospital from 2017 to 2018 were selected to detect 25-hydroxyvitamin D (25(OH)D) level in peripheral blood. According to the 25(OH)D level

all children were divided into the vitamin D deficiency group (n=60) and the normal group (n=550). The influencing factors of vitamin D deficiency were analyzed

and behavioral interventions were developed. The vitamin D deficiency group was divided into the behavioral intervention group (behavioral intervention + vitamin D drops and calcium gluconate zinc oral solution) and the conventional treatment group (vitamin D drops and calcium gluconate zinc oral solution) according to the random number table

with 30 cases in each group. The clinical efficacy and changes of bone metabolism related indicators before and after treatment in the intervention group and the conventional treatment group were compared. Results: Feeding patterns

outdoor activity time

anorexia

diarrhea and vitamin D deficiency were associated (P<0.05). Logistic analysis showed that feeding patterns

outdoor activity time and diarrhea were independent influencing factors of vitamin D deficiency (P<0.05). Children with ordinary milk powder or other feeding patterns

outdoor activity time <2 h/d

frequent diarrhea were more likely to have vitamin D deficiency. Before treatment

there was no significant difference in 25(OH)D level and bone metabolism related indicators between the behavioral intervention group and the conventional treatment group (P>0.05). After 2 months of treatment

25(OH)D level

serum calcium

squamous and osteocalcin in the behavioral intervention group were higher than those in the conventional treatment group

and bone alkaline phosphatase (BALP) was lower than that in the conventional treatment group

the difference was statistically significant (P<0.05). Conclusion: On the basis of drug treatment

behavioral interventions combined with feeding patterns

digestive tract function and outdoor activity time can promote the clinical efficacy of vitamin D deficiency and improve bone metabolism related indicators.