Analysis of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections in 104 Children

Xu Jian; Tang Zhihua

doi:10.13407/j.cnki.jpp.1672-108X.2024.01.006

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Analysis of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections in 104 Children

更新时间：2024-01-12

- Analysis of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections in 104 Children
- Vol. 30, Issue 1, Pages: 21-23(2024)
- 作者机构：
  
  绍兴市人民医院,浙江,绍兴,312000
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2024.01.006
  CLC：
- Published：2024，
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Xu Jian, Tang Zhihua. Analysis of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections in 104 Children. [J]. 30(1):21-23(2024)
DOI：

Xu Jian, Tang Zhihua. Analysis of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections in 104 Children. [J]. 30(1):21-23(2024) DOI： 10.13407/j.cnki.jpp.1672-108X.2024.01.006.

摘要

目的:分析儿童中药注射剂不良反应(ADR)发生情况

为临床合理用药提供参考。方法:从国家药品ADR 监测系统中收集2006-2021 年中成药不良反应案例1 356 例

筛选出中药注射剂在儿童中发生的ADR 共104 例。从患儿因素、药物因素及临床因素3 个角度对ADR 的特点及原因进行分析。结果:男65 例(62. 50%)

女39 例(37. 50%);≤5 岁59 例(56. 73%);复方制剂63 例(60. 58%)

单一组分制剂41 例(39. 42%);用药后30 min 内发生ADR 86 例(82. 69%)。结论:儿童尚处于生长发育阶段

需要重视中药注射剂在儿童中的应用

谨慎用药

加强监测

以减少或避免ADR 的发生。

Abstract

Objective: To analyze the occurrence of adverse drug reactions (ADR) induced by traditional Chinese medicine injections in children

so as to provide reference for rational drug use in clinic. Methods: A total of 1

356 cases of ADR induced by Chinese patent medicines were collected from the National ADR Monitoring System from 2006 and 2021. Totally 104 cases of ADR induced by traditional Chinese medicine injections in the pediatric population were selected for analysis. The characteristics and causes of ADR were analyzed from three perspectives: patient factors

drug factors and clinical factors. Results: Of the 104 cases

65 cases (62. 50%) were males and 39 cases (37. 50%) were females. In the age group of ⩽5 years

there were 59 cases (56. 73%). Composite formulations accounted for 63 cases (60. 58%)

while single-component formulations accounted for 41 cases (39. 42%). ADR occurred within 30 minutes after administration in 86 cases (82. 69%). Conclusion: As children are still in the stage of growth and development

attention should be paid to the use of traditional Chinese medicine injections. Prudent drug use

enhanced monitoring

and measures to reduce or avoid ADR are recommended.

关键词

儿童中成药中药注射剂不良反应

Keywords

childrenChinese patent medicinestraditional Chinese medicine injectionsadverse drug reactions

references

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