Objective: To explore the clinical characteristics

diagnosis and treatment of Kawasaki disease in neonates. Methods: Retrospective analysis was conducted on a case of neonatal Kawasaki disease admitted into the department of neonatology of Children’s Hospital

Zhejiang University School of Medicine. The clinical manifestations

laboratory examinations

treatment course and relevant literature were reviewed. Results: The child

female

29 d

was admitted into the hospital on Jun. 8

2017 for 3 d of fever. Physical examination revealed coarse breath sounds in both lungs

audible rales

cool extremities

and rash on the lower limbs. Auxiliary examinations showed white blood cell count of 5. 27×109/ L

neutrophil percentage of 75. 8%

hemoglobin of 100 g / L

platelet of 112×109/ L

highly sensitive C-reactive protein of 60 mg / L

and chest X-ray suggested pneumonia. The child received anti-infective therapy upon admission

yet the fever persisted. A red rash appeared on the face

accompanied by conjunctival congestion and swelling of the fingers and toes. Intravenous immunoglobulin and symptomatic treatment with oral aspirin were administered

leading to improvement in the disease condition. Two consecutive cardiac ultrasounds did not reveal coronary artery injury

and the child was discharged with improved clinical status. Conclusion: Kawasaki disease in neonates often presents with atypical symptoms and requires early identification and treatment.