Cost-Benefit Analysis of Bacterial Lysates for Recurrent Respiratory Tract Infections in Children

Cao Wang; Liu Shui; Wang Qiang; Cai Yanrong; Yu Yuncui; Jia Lulu; Wang Xiaoling

doi:10.13407/j.cnki.jpp.1672-108X.2023.05.003

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Cost-Benefit Analysis of Bacterial Lysates for Recurrent Respiratory Tract Infections in Children

更新时间：2023-05-19

- Cost-Benefit Analysis of Bacterial Lysates for Recurrent Respiratory Tract Infections in Children
- Vol. 29, Issue 5, Pages: 10-13(2023)
- 作者机构：
  
  1. 国家儿童医学中心,首都医科大学附属北京儿童医院,北京,100045
  2. 应急总医院,北京,100028
  3. 北京普瑞快思医药咨询有限公司,北京,100025
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2023.05.003
  CLC：
- Published：2023，
  
  Published Online：10 May 2023，
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Cao Wang, Liu Shui, Wang Qiang, et al. Cost-Benefit Analysis of Bacterial Lysates for Recurrent Respiratory Tract Infections in Children. [J]. 29(5):10-13(2023)
DOI：

Cao Wang, Liu Shui, Wang Qiang, et al. Cost-Benefit Analysis of Bacterial Lysates for Recurrent Respiratory Tract Infections in Children. [J]. 29(5):10-13(2023) DOI： 10.13407/j.cnki.jpp.1672-108X.2023.05.003.

摘要

目的:评估细菌溶解产物(泛福舒)联合常规治疗预防儿童反复呼吸道感染(RRTI)的经济性。方法:采用成本-效益分析法

计算RRTI 患儿加用泛福舒后的增量成本和增量效益

从而计算净效益。采用专家访谈和问卷调研

收集相关的成本和费用参数。结果:共计访谈8 名临床医师

收集相关参数进行分析。结果显示

在6 个月随访期内

如果使用1 个疗程泛福舒

能减少1. 96 次RRTI

增量成本为199. 59 元

增量效益为4 601. 98 元

净效益为4 402. 39 元

即每增加1 元的投入

将获得增量净效益22. 06 元。敏感性分析显示结果稳定。结论:在常规治疗基础上加用泛福舒对防治儿童RRTI 具有经济性

但未来仍需要真实世界数据补充和验证相关结论。

Abstract

Objective: To evaluate the economic feasibility of using bacterial lysates (Broncho-Vaxom) combined with conventional therapy for treating recurrent respiratory tract infections (RRTI) in children. Methods: Cost-benefit analysis was used to calculate the net benefit by comparing the incremental cost and benefit in RRTI children after using bacterial lysates. Expert interviews and questionnaires were conducted for collecting relevant cost and expense parameters. Results: A total of 8 clinicians received the interview and completed the questionnaire

and the collected parameters were analyzed. The results showed that using one course of Broncho- Vaxom could reduce 1. 96 times of RRTI during 6-month follow-up. The incremental cost was about 199. 59 yuan

while with an incremental benefit of 4

601. 98 yuan

which achieved 4

402. 39 yuan in net benefit. This means that for every additional yuan invested

a net benefit of 22. 06 yuan can be obtained. Sensitivity analysis also showed the robustness and reliability. Conclusion: The combined use of bacterial lysates has cost-benefit for the prevention and treatment of RRTI in children. More real-world evidence and data still be needed to supplement and validate the conclusions in the future.

关键词

细菌溶解产物反复呼吸道感染儿童成本效益分析

Keywords

bacterial lysaterecurrent respiratory tract infectionchildrencost-benefit analysis

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