Drug Therapy Analysis of Clinical Pharmacist Participating in a Case of Intracranial Aspergillus Infection

He Dan; Cao Qing; Jiang Yuelian; Zhang Shunguo

doi:10.13407/j.cnki.jpp.1672-108X.2023.04.004

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Drug Therapy Analysis of Clinical Pharmacist Participating in a Case of Intracranial Aspergillus Infection

更新时间：2023-04-28

- Drug Therapy Analysis of Clinical Pharmacist Participating in a Case of Intracranial Aspergillus Infection
- Vol. 29, Issue 4, Pages: 13-17(2023)
- 作者机构：
  
  上海交通大学医学院附属上海儿童医学中心,上海,200127
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2023.04.004
  CLC：
- Published：2023，
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He Dan, Cao Qing, Jiang Yuelian, et al. Drug Therapy Analysis of Clinical Pharmacist Participating in a Case of Intracranial Aspergillus Infection. [J]. 29(4):13-17(2023)
DOI：

He Dan, Cao Qing, Jiang Yuelian, et al. Drug Therapy Analysis of Clinical Pharmacist Participating in a Case of Intracranial Aspergillus Infection. [J]. 29(4):13-17(2023) DOI： 10.13407/j.cnki.jpp.1672-108X.2023.04.004.

摘要

目的:探讨儿科临床药师在肥胖患儿颅内曲霉菌感染治疗中的作用。方法:临床药师通过参与1 例肥胖患儿颅内曲霉菌感染的药物治疗实践

调整肥胖患儿用药方案

监测抗真菌药物血药浓度、检测代谢基因并调整剂量

降低了药物不良反应发生率。结果:经过1 个月抗感染治疗

患儿病情好转出院。结论:对于罕见颅内曲霉菌感染肥胖患儿

临床药师进行了个体化药物治疗

保障了儿童用药的安全性和有效性。

Abstract

Objective: To explore the role of clinical pharmacists in the treatment of intracranial Aspergillus infection in obese children. Methods: Clinical pharmacists participated in the drug therapy of intracranial Aspergillus infection in an obese child

recommended the initial dose of the obese child

monitored the blood concentration of voriconazole

detected metabolic genes and adjusted the dose

which reduced the incidence of adverse drug reactions related to voriconazole. Results: After 1 month of anti-infection treatment

the child was discharged from hospital with improved condition. Conclusion: For rare intracranial Aspergillus infection

clinical pharmacists should carry out individualized drug therapy for obese children to ensure the medication safety and effectiveness for children.

关键词

临床药师儿童肥胖曲霉菌

Keywords

clinical pharmacistchildrenobesityAspergillus

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