Effect of Intravenous Immunoglobulin on Hepatitis B Core Antibody in Neonates

Yang Lin; Yang Guang; Deng Tao

doi:10.13407/j.cnki.jpp.1672-108X.2023.03.013

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Effect of Intravenous Immunoglobulin on Hepatitis B Core Antibody in Neonates

更新时间：2023-04-14

- Effect of Intravenous Immunoglobulin on Hepatitis B Core Antibody in Neonates
- Vol. 29, Issue 3, Pages: 48-50(2023)
- 作者机构：
  
  攀枝花市妇幼保健院,四川,攀枝花,617000
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2023.03.013
  CLC：
- Published：2023，
  
  Published Online：10 March 2023，
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Yang Lin, Yang Guang, Deng Tao. Effect of Intravenous Immunoglobulin on Hepatitis B Core Antibody in Neonates. [J]. 29(3):48-50(2023)
DOI：

Yang Lin, Yang Guang, Deng Tao. Effect of Intravenous Immunoglobulin on Hepatitis B Core Antibody in Neonates. [J]. 29(3):48-50(2023) DOI： 10.13407/j.cnki.jpp.1672-108X.2023.03.013.

摘要

目的:探讨新生儿使用静注人免疫球蛋白(IVIG)后乙肝核心抗体(HBcAb)的变化。方法:采用回顾性研究方法

收集我院2019-2020 年使用IVIG 的住院新生儿病历

分析使用IVIG 前后患儿HBcAb 的变化。结果:共收集43 例患儿

其中5 例使用 IVIG 前后HBcAb 均呈阳性

10 例使用IVIG 前后HBcAb 均呈阴性

18 例使用IVIG 后HBcAb 由阴性转为阳性

10 例使用IVIG 后因未进行乙肝5 项复测未知HBcAb 的变化。结论:输注IVIG 会引起新生儿HBcAb 水平升高

提示对输注IVIG 的患儿进行抗体被动转移的排除具有重要意义。

Abstract

Objective: To investigate the changes of hepatitis B core antibody (HBcAb) in newborns after intravenous immunoglobulin (IVIG). Methods: Retrospective research method was conducted in this study to collect medical records of newborns who had IVIG in our hospital from 2019 to 2020

and the changes of HBcAb before and after using IVIG were compared. Results: Among 43 hospitalized children treated with IVIG

5 children were HBcAb positive before IVIG treatment; HBcAb was still negative in 10 children after IVIG treatment; HBcAb was positive in 18 children after IVIG;10 children were not retested for hepatitis B after IVIG

so the changes of HBcAb were unknown. Conclusion: Infusion of IVIG can increase the level of HBcAb in neonates

which suggests that it is of great significance to eliminate passive transfer of antibodies in neonates with IVIG.

关键词

静注人免疫球蛋白乙肝核心抗体抗体被动转移

Keywords

ntravenous immunoglobulinhepatitis B core antibodypassive antibody transfer

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