Pharmaceutical Care for a Child with Bloodstream and Abdominal Infection Induced by Carbapenem Resistant Escherichia Coli after Liver Transplantation

Jin Hairong; Song Yanqing; Liang Xiaoyu; Ma Jie

doi:10.13407/j.cnki.jpp.1672-108X.2022.12.003

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Pharmaceutical Care for a Child with Bloodstream and Abdominal Infection Induced by Carbapenem Resistant Escherichia Coli after Liver Transplantation

更新时间：2023-04-16

- Pharmaceutical Care for a Child with Bloodstream and Abdominal Infection Induced by Carbapenem Resistant Escherichia Coli after Liver Transplantation
- Vol. 28, Issue 12, Pages: 7-10(2022)
- 作者机构：
  
  吉林大学第一医院,吉林,长春,130021
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2022.12.003
  CLC：
- Published：2022，
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Jin Hairong, Song Yanqing, Liang Xiaoyu, et al. Pharmaceutical Care for a Child with Bloodstream and Abdominal Infection Induced by Carbapenem Resistant Escherichia Coli after Liver Transplantation. [J]. 28(12):7-10(2022)
DOI：

Jin Hairong, Song Yanqing, Liang Xiaoyu, et al. Pharmaceutical Care for a Child with Bloodstream and Abdominal Infection Induced by Carbapenem Resistant Escherichia Coli after Liver Transplantation. [J]. 28(12):7-10(2022) DOI： 10.13407/j.cnki.jpp.1672-108X.2022.12.003.

摘要

目的：探讨临床药师在肝移植术后患儿抗感染治疗中的作用。方法：1例8个月患儿肝移植术后合并耐碳青酶烯大肠埃希菌致血流和腹腔感染，经临床药师多次会诊，优化抗感染药物治疗方案，并结合患儿情况，提出美罗培南大剂量用药且延长时间泵入的建议，根据患儿病情变化加用阿米卡星、复方磺胺甲噁唑治疗，同时规避药物相互作用和关注药物不良反应。结果：抗感染治疗有效，患儿治愈出院。结论：临床药师发挥专长，协助医师制定治疗方案，对特殊人群的抗感染治疗进行密切监护，提高了临床药物治疗的有效性和安全性。

Abstract

Objective: To probe into the role of clinical pharmacists in anti-infective therapy of a child after liver transplantation. Method: For an 8-month child with bloodstream and abdominal infection induced by carbapenem resistant Escherichia coli after liver transplantation

clinical pharmacists optimized the anti-infective therapy regimen after several times of consultations

suggested high-dose meropenem with prolonged pumping time

and added amikacin and compound sulfamethoxazole according to the child’s condition

while avoiding drug interactions and paying attention to adverse drug reactions. Results: The anti-infective therapy was effective and the child was cured and discharged. Conclusion: Clinical pharmacists give full play to their expertise to assist clinicians in formulating treatment regimens and closely monitor the anti-infective therapy in special populations

thus improving the efficacy and safety of clinical drug therapy.

关键词

肝移植抗感染治疗临床药师药学监护

Keywords

liver transplantationanti-infective therapyclinical pharmacistspharmaceutical care

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