A Case Report of Liver Failure in a Child Induced by Ibuprofen

Wang Juping; Li Zhiling; Liu Hongxia; Huang Jianquan

doi:10.13407/j.cnki.jpp.1672-108X.2022.11.008

您当前的位置：

首页 >

文章列表页 >

A Case Report of Liver Failure in a Child Induced by Ibuprofen

更新时间：2023-04-14

- A Case Report of Liver Failure in a Child Induced by Ibuprofen
- Vol. 28, Issue 11, Pages: 28-31(2022)
- 作者机构：
  
  1. 上海市儿童医院，上海交通大学医学院附属儿童医院,上海,200062
  2. 河南省儿童医院,郑州,450000
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2022.11.008
  CLC：
- Published：2022，
扫描看全文
Wang Juping, Li Zhiling, Liu Hongxia, et al. A Case Report of Liver Failure in a Child Induced by Ibuprofen. [J]. 28(11):28-31(2022)
DOI：

Wang Juping, Li Zhiling, Liu Hongxia, et al. A Case Report of Liver Failure in a Child Induced by Ibuprofen. [J]. 28(11):28-31(2022) DOI： 10.13407/j.cnki.jpp.1672-108X.2022.11.008.

摘要

目的：分析布洛芬致儿童肝衰竭病例的药物治疗方法，探索临床药师在药物治疗监护中的作用。方法：分析1例由布洛芬引起儿童急性肝衰竭患儿的临床资料，并结合相关文献对治疗方案进行讨论。结果：针对患儿出现肝衰竭情况，使用血浆置换、复方甘草酸苷、多烯磷脂酰胆碱、熊去氧胆酸、头孢他啶及白蛋白等治疗，患儿症状得到明显好转。结论：布洛芬导致的肝损伤一般轻微可逆，但如果发现其导致严重肝损伤的情况应及时治疗。因治疗药物也会存在进一步导致肝损伤的可能，故应密切检测肝功能指标，合理选择治疗药物

Abstract

Objective: To analyze the drug treatment methods of liver failure in a child induced by ibuprofen

so as to explore the role of clinical pharmacists in drug treatment monitoring. Methods: The clinical data of a child with acute liver failure induced by ibuprofen were analyzed

and the treatment regimen was discussed in combination with relevant literature. Results: According to the conditions of liver failure

plasma exchange detoxification

compound glycyrrhizin

polyene phosphatidyl choline

ceftazidime and albumin were used

and the symptoms of the child were significantly improved. Conclusion: Liver injury induced by ibuprofen is generally mild and reversible

yet if it is found to induce severe liver injury

the liver injury should be treated promptly. Due to therapeutic drugs also have the potential to induce further liver injury

liver function indicators should be closely tested and therapeutic drugs should be selected rationally

关键词

布洛芬肝衰竭药学监护儿童

Keywords

buprofenliver failurepharmaceutical carechildren

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Analysis of Pharmaceutical Care on the Use of Voriconazole in Pediatric Liver Transplantation Patients Younger Than 2 Years of Age

Treatment of Cerebral Venous Thrombosis in a Child with Warfarin Based on Gene Polymorphism

Pharmaceutical Care for One Child with Refractory Mycoplasma Pneumoniae Pneumonia Complicated with Pulmonary Embolism by Clinical Pharmacists

Individualized Pharmaceutical Care for a Child with Infective Endocarditis and Osteomyelitis

Pharmaceutical Care for Catheter-Related Bloodstream Infection in Two Children with Intermittent Hemodialysis

Related Author

Wang Weina

Cheng Sheng

Wei Hongtao

Shen Su

Luo Ping

Zhang Hui

He Weiwen

Qu Qiang

Related Institution

Beijing Friendship Hospital, Capital Medical University

Xiangya Hospital, Central South University

Shanghai Children’s Hospital, Children’s Hospital of Shanghai Jiaotong University

The Second Hospital of Jilin University

Jilin University Hospital

⁰