Report of 10 Cases of Incomplete Kawasaki Disease with Non-Infectious Diarrhea Onset

Shao Hui; Wang Na

doi:10.13407/j.cnki.jpp.1672-108X.2022.09.011

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Report of 10 Cases of Incomplete Kawasaki Disease with Non-Infectious Diarrhea Onset

更新时间：2022-11-04

- Report of 10 Cases of Incomplete Kawasaki Disease with Non-Infectious Diarrhea Onset
- Vol. 28, Issue 9, Pages: 41-44(2022)
- 作者机构：
  
  武汉市第一医院,武汉,430000
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2022.09.011
  CLC：
- Published：2022，
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Shao Hui, Wang Na. Report of 10 Cases of Incomplete Kawasaki Disease with Non-Infectious Diarrhea Onset. [J]. 28(9):41-44(2022)
DOI：

Shao Hui, Wang Na. Report of 10 Cases of Incomplete Kawasaki Disease with Non-Infectious Diarrhea Onset. [J]. 28(9):41-44(2022) DOI： 10.13407/j.cnki.jpp.1672-108X.2022.09.011.

摘要

目的：探讨临床上以非感染性腹泻起病的不完全川崎病（IKD）的临床特点及诊断依据，以早期发现并诊治，减少心血管系统并发症的发生及改善预后。方法：回顾性分析2016年12月至2020年6月我院儿科10例以非感染性腹泻起病的IKD患儿的临床资料及实验室检查结果。结果：以非感染性腹泻起病的IKD主要临床表现为无明显诱因出现反复腹泻、发热，渐出现结膜充血、口唇皲裂、浮肿、贫血、肛周脱皮；实验室检查中，C反应蛋白、降钙素原、血清淀粉样蛋白、血沉、血小板明显增高；持续监测心脏彩超可见冠状动脉病变。结论：以非感染性腹泻起病的IKD早期临床表现以反复腹泻、发热为主，粪便培养、血培养无阳性发现，实验室检查炎症指标明显增高，但住院治疗过程中抗感染疗效欠佳，此时均应尽早行心脏彩超检查，尽早明确IKD临床诊断，及早治疗，减少冠脉病变发生。

Abstract

Objective: To probe into the clinical features and diagnostic basis of incomplete Kawasaki disease (IKD) with non-infectious diarrhea onset

and to provided early detection and treatment

reduce the cardiovascular system complications and improve the prognosis. Methods: Clinical data and laboratory results of 10 IKD children with non-infectious diarrhea onset in pediatrics of our hospital from Dec. 2016 to Jun. 2020 were retrospectively analyzed. Results: The main clinical manifestations of IKD with non-infectious diarrhea onset were repeated diarrhea

fever

conjunctival congestion

chapped lips

edema

anemia and perianal peeling. Laboratory examinations showed C-reactive protein

procalcitonin

serum amyloid protein

erythrocyte sedimentation rate and platelet increased significantly

and coronary artery disease could be seen by continuous monitoring of cardiac color Doppler echocardiography. Conclusion: The early clinical manifestations of IKD with non-infectious diarrhea onset are mainly repeated diarrhea and fever

with no positive results in stool and blood culture. Laboratory examinations shows that the inflammatory factors increase significantly. During hospitalization

the effect of anti-infection is not satisfied

color Doppler echocardiography should be performed as early as possible

clinical diagnosis of IKD should be confirmed as soon as possible

and early treatment should be carried out to reduce the occurrence of coronary artery disease.

关键词

非感染性腹泻发热冠脉扩张不完全川崎病

Keywords

non-infectious diarrheafevercoronary artery dilatationncomplete Kawasaki disease

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