Objective: To explore the status of medication adherence in children with epilepsy and analyze its influencing factors. Methods: Children with epilepsy admitted into outpatient or inpatient department of our hospital from Jan. to Sept. 2021 were extracted

and the Morisky medication adherence questionnaire

self-designed questionnaire on the general data of children with epilepsy

and the questionnaire on medication knowledge

medication belief and medication support of guardians were completed by the guardians of children with epilepsy on a voluntary basis

and the factors influencing medication adherence were analyzed by multi-factor Logistic regression. Results: A total of 107 valid questionnaires were collected through the WeChat platform

the age of the children was (6.75±2.76) years

the medication adherence level was (6.42±1.20) points

the medication adherence was low in 34 cases (31.78%)

medium in 54 cases (50.47%) and high in 19 cases (17.76%). The medication knowledge score of the guardians was (19.85±4.77) points

and 56.07% of the medication knowledge of the guardians was at the medium level. And 30.84% of the medication belief of the guardians was at the low level

considering that the harm of medication outweighed the benefit; 31.78% of the guardians had poor medication support behavior. Logistic regression analysis showed that medication support affects medication adherence (OR=1.225

P=0.034). Conclusion: As a chronic disease

the medication adherence of most children with epilepsy needs to be improved

mainly due to the omission of drugs

unauthorized change of drug dose

and the reduction or discontinuation of drugs by the guardians of the children for fear of adverse drug reactions. Improvement on medication support of the guardians for the children plays an important role in improving the medication adherence of the children.