Analysis of 184 Cases of Adverse Drug Reactions in Children in a Hospital from 2016 to 2018

Huang Yunling; Deng Benyong; Cai Huajing

doi:10.13407/j.cnki.jpp.1672-108X.2021.04.014

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Analysis of 184 Cases of Adverse Drug Reactions in Children in a Hospital from 2016 to 2018

更新时间：2022-11-03

- Analysis of 184 Cases of Adverse Drug Reactions in Children in a Hospital from 2016 to 2018
- Vol. 27, Issue 4, Pages: 46-48(2021)
- 作者机构：
  
  福建省福州儿童医院,福建,福州,350005
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2021.04.014
  CLC：
- Published：2021，
  
  Published Online：10 April 2021，
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Huang Yunling, Deng Benyong, Cai Huajing. Analysis of 184 Cases of Adverse Drug Reactions in Children in a Hospital from 2016 to 2018. [J]. 27(4):46-48(2021)
DOI：

Huang Yunling, Deng Benyong, Cai Huajing. Analysis of 184 Cases of Adverse Drug Reactions in Children in a Hospital from 2016 to 2018. [J]. 27(4):46-48(2021) DOI： 10.13407/j.cnki.jpp.1672-108X.2021.04.014.

摘要

目的：了解某儿童医院药品不良反应（ADR）发生的规律和特点，为促进临床合理用药、保障儿童用药安全提供参考。方法：采用回顾性分析方法，收集2016-2018年上报的184例ADR报告进行统计分析。结果：184例ADR中，男103例（55.98%），女81例（44.02%）；1~6岁年龄组ADR发生率最高（60.33%）；引发ADR最多的药品种类为抗感染药（38.18%）；ADR最常见的临床表现为皮疹、斑丘疹、瘙痒（44.71%）；注射用重组人生长激素上报新的ADR例次最多；严重ADR主要表现为骨髓抑制。结论：应加强对儿童ADR的监测，以减少或避免其发生。

Abstract

Objective: To investigate the regularities and characteristics of adverse drug reaction (ADR) in a children’s hospital

so as to promote the rational drug use in clinic and ensure the safety of drug use in children. Methods: Retrospective method was adopted

a total of 184 ADR reports from 2016 to 2018 were collected for statistical analysis. Results: Among 184 ADR reports

103 cases were males (55.98%) and 81 cases were females (44.02%). The incidence of ADR was the highest in the age group from 1 to 6 years (60.33%). Most ADR was induced by anti-infective drugs (38.18%). The most common clinical manifestations of ADR were skin rash

maculopapular rash and itching (44.71%). Recombinant human growth hormone for injection had reported the most new ADR cases. Severe ADR was mainly manifested as bone marrow suppression induced by anti-tumor drugs. Conclusion: More attention should be paid to the monitoring of ADR for children

so as to reduce or avoid the occurrence of ADR.

关键词

儿童药品不良反应分析

Keywords

childrenadverse drug reactionsanalysis

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