Efficacy of Oseltamivir Granules Combined with Lanqin Oral Liquid in the Treatment of Early Influenza A in Children

Chu Kaidong; Ji Fenghua

doi:10.13407/j.cnki.jpp.1672-108X.2021.04.010

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Efficacy of Oseltamivir Granules Combined with Lanqin Oral Liquid in the Treatment of Early Influenza A in Children

更新时间：2022-11-03

- Efficacy of Oseltamivir Granules Combined with Lanqin Oral Liquid in the Treatment of Early Influenza A in Children
- Vol. 27, Issue 4, Pages: 34-37(2021)
- 作者机构：
  
  南通大学附属海安医院，江苏海安,226600
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2021.04.010
  CLC：
- Published：2021，
  
  Published Online：10 April 2021，
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Chu Kaidong, Ji Fenghua. Efficacy of Oseltamivir Granules Combined with Lanqin Oral Liquid in the Treatment of Early Influenza A in Children. [J]. 27(4):34-37(2021)
DOI：

Chu Kaidong, Ji Fenghua. Efficacy of Oseltamivir Granules Combined with Lanqin Oral Liquid in the Treatment of Early Influenza A in Children. [J]. 27(4):34-37(2021) DOI： 10.13407/j.cnki.jpp.1672-108X.2021.04.010.

摘要

目的：探讨小儿早期甲型流感的有效治疗方法。方法：将240例早期甲型流感患儿按就诊日期的单双数分为对照组和观察组各120例，对照组采用磷酸奥司他韦颗粒治疗，2.0~2.5 mg/kg，温开水冲服，每天2次，观察组在对照组基础上联合蓝芩口服液，2~5岁每次5mL，>5岁每次10mL。，每天3次治疗，两组均治疗5 d为1个疗程，观察两组患儿的症状恢复情况、药物不良反应及总体疗效。结果：观察组患儿的发热、咽痛、肌痛和卡他症状消失时间均短于对照组，治疗5 d后的hs-CRP、IL-6和MCP-1等炎症指标水平均低于对照组，总有效率高于对照组，并发症发生率、危重病例比例和住院比例均低于对照组（P均<0.05），两组药物不良反应发生率比较差异无统计学意义（P>0.05）。结论：在磷酸奥司他韦颗粒治疗基础上联合蓝芩口服液辅助治疗小儿早期甲型流感，能快速控制临床症状，改善炎症指标，提高疗效，改善预后，且用药安全。

Abstract

Objective: To probe into the effective treatment method of early influenza A in children. Methods: Totally 240 children with early influenza A were divided into the control group and the observation group according to the visit sequence

with 120 cases in each group. The control group was treated with oseltamivir phosphate granules

from 2.0 to 2.5 mg/kg in warm boiled water

twice a day

while the observation group received Lanqin oral liquid on the basis of the control group

5 mL for 2 to 5 years old

10 mL for > for 5 years old

3 times a day according to the age. Both groups were treated for 5 d as a course of treatment. The recovery of symptoms

adverse drug reactions and overall efficacy of two groups were observed. Results: The disappearance time of fever

sore throat

myalgia and catarrhal symptoms in the observation group was shorter than that in the control group

and the levels of inflammation indicators such as hs-CRP

IL-6 and MCP-1 were lower than those in the control group after 5 d of treatment

the total effective rate was higher than that of the control group

and the incidence of complications

the proportion of critically ill cases

and the proportion of hospitalizations were lower than those of the control group (P<0.05). There was no significant difference in the incidence of adverse drug reactions between two groups (P>0.05). Conclusion: Oseltamivir phosphate granules combined with Lanqin oral liquid in the treatment of early influenza A in children can rapidly control the clinical symptoms

improve the inflammatory indicators and the efficacy

promote the prognosis of the disease with higher safety.

关键词

儿童甲型流感奥司他韦颗粒蓝芩口服液

Keywords

childrennfluenza Aoseltamivir granulesLanqin oral liqu

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