Objective: To explore the basal rate delivery of insulin pump in preschool children with newly diagnosed type 1 diabetes

so as to improve parents’ confidence in blood glucose control. Methods: Clinical data of children from 3 to 6 years with newly onset type1 diabetes in Children’s Hospital Affiliated to Zhengzhou University from Sept. 2013 to Mar. 2017 were collected. All children were treated with subcutaneous insulin pump immediately or after the correction of ketoacidosis. The standard diet was formulated in accordance with the food exchange portion. The initial total daily insulin dosage in insulin pump was from 0.8 to 1.0 IU/kg. The initial insulin pump basal rate was set to 50% of the total insulin dosage and divided into 7 segments based on clinical experience. The blood glucose was monitored 8 times a day. The time cut-off point was selected as the blood glucose reached the target level and the basal rate of insulin pump did not change for 2 d. Meanwhile

relevant data of the children were collected for statistical analysis. Results: A total of 30 children were enrolled in this study

including 18 males and 12 females. The dose of insulin pump basal rate was the lowest from 0:00 to 6:00

and the highest from 16:00 to 20:00. Conclusion: The dawn phenomenon of newly-onset type 1 diabetes in preschool children is not significant. When setting the basal rate delivery of insulin pump

attention should be paid to the characteristics of the basal insulin pump rate in preschool children.