Object: To analyse the application rationality of omeprazole enteric-coated tablets in pediatrics

so as to provide reference for the rational drug use in clinic. Methods: With reference to the guidelines for adult use of proton mercury inhibitors (PPIs)

relevant literature and drug instructions

the application irrationality of omeprazole enteric-coated tablets in pediatrics of Zigong First People’s Hospital from 2016 to 2017 was summarized and the countermeasures were proposed. Results: From 2016 to 2017

there were 87 cases (67.97%) of irrational application of omeprazole enteric-coated tablets in pediatrics of our hospital

among which 62 cases (71.26%) had no indications

and 25 cases (28.74%) had irrational dosage. Conclusion: The irrational application rate of omeprazole enteric-coated tablets is relatively high

which leads to high treatment risks. The triggers are blind medication

inaccurate medication and insufficient participation of clinical pharmacists. In clinical medication

the indications should be clear

and the drugs should be selected rationally

the dosage should be clear to ensure the safety and effectiveness of medication

and the pharmacists are supposed to participate into the guidance and improve the rationality of medication.