Sufentanil Combined with Dexamethasone in Postoperative Intravenous Self-Controlled Analgesia in Children

Zhou Yanling; Hu Haiyou; Lin Sen; Chen Lingjun

doi:10.13407/j.cnki.jpp.1672-108X.2021.01.009

您当前的位置：

首页 >

文章列表页 >

Sufentanil Combined with Dexamethasone in Postoperative Intravenous Self-Controlled Analgesia in Children

更新时间：2022-11-03

- Sufentanil Combined with Dexamethasone in Postoperative Intravenous Self-Controlled Analgesia in Children
- Vol. 27, Issue 1, Pages: 27-30(2021)
- 作者机构：
  
  海口市人民医院,海南,海口,570208
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2021.01.009
  CLC：
- Published：2021，
  
  Published Online：10 January 2021，
扫描看全文
Zhou Yanling, Hu Haiyou, Lin Sen, et al. Sufentanil Combined with Dexamethasone in Postoperative Intravenous Self-Controlled Analgesia in Children. [J]. 27(1):27-30(2021)
DOI：

Zhou Yanling, Hu Haiyou, Lin Sen, et al. Sufentanil Combined with Dexamethasone in Postoperative Intravenous Self-Controlled Analgesia in Children. [J]. 27(1):27-30(2021) DOI： 10.13407/j.cnki.jpp.1672-108X.2021.01.009.

摘要

目的：探讨舒芬太尼联合地塞米松在小儿术后静脉自控镇痛的应用价值。方法：选择ASA Ⅰ~Ⅱ级择期手术全身麻醉术后患儿84例，随机分为对照组和试验组各42例。对照组采用舒芬太尼进行术后镇痛，试验组采用舒芬太尼联合地塞米松，观察两组患儿术后2 h、6 h、12 h、24 h、48 h生命体征指标，如呼吸频率（RR）、心率（HR）、平均动脉压（MAP）、血氧饱和度（SPO2）等。采用视觉模拟评分法（VAS）、最新改良镇静评分（Ramsay评分）评价术后药物的镇静镇痛效果，并记录术后药物不良反应。结果：两组患儿术后各时点的RR、MAP、HR、SpO2比较差异均无统计学意义（P均>0.05）。试验组患儿的术后VAS评分低于对照组，而Ramsay评分高于对照组，且呼吸抑制、皮肤瘙痒、恶心呕吐、眩晕及尿潴留等不良反应发生率均低于对照组（P均<0.01）。结论：与单用舒芬太尼进行术后镇痛相比，舒芬太尼联合地塞米松可显著提高镇痛镇静效果，且对呼吸抑制作用较弱，不良反应较少。

Abstract

Objective: To explore the clinical application value of sufentanil combined with dexamethasone in the treatment of postoperative intravenous self-controlled analgesia in children. Methods: Totally 84 children with general anesthesia of American Society of Anesthesiologists (ASA) Ⅰ to Ⅱ were randomly divided into the control group and the experimental group

with 42 cases in each group. The control group was treated with sufentanil

while the experimental group received sufentanil combined with dexamethasone. The vital signs such as respiratory rate (RR)

heart rate (HR)

mean arterial pressure (MAP) and blood oxygen saturation (SpO2) were observed after surgery of 2 h

6 h

12 h

24 h and 48 h. Visual analogue scale (VAS) and latest modified sedation score (Ramsay) were used to evaluate the sedative and analgesic effects of postoperative drugs

and adverse drug reactions were recorded. Results: There was no significant difference in RR

MAP

HR and SpO2 between two groups (P>0.05). Postoperative VAS score and Ramsay score in the experimental group were lower than those in the control group

and incidence of adverse drug reactions such as respiratory inhibition

skin itching

nausea and vomiting

dizziness and urinary retention were lower than those in the control group (P<0.01). Conclusion: Compared with sufentanil alone for postoperative analgesia

sufentanil combined with dexamethasone can significantly improve the analgesic and sedative effects

and has weaker respiratory depression and fewer adverse drug reactions.

关键词

舒芬太尼地塞米松儿童术后疼痛自控镇痛

Keywords

sufentanilexamethasonechildrenpainself-control analgesia

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Comparison of Efficacy and Safety of Dexamethasone Versus Methylprednisolone in the Treatment ofChildren with Refractory Mycoplasma Pneumoniae Pneumonia

Efficacy of Different Administration Methods and Doses of Glucocorticoid in the Treatment of Children with Acute Infectious Laryngitis

Analysis of 36 Cases of Drug Poisoning in Children in a Grade III, Level A General Hospital andConsideration on Pharmaceutical Care

Application of Dexmedetomidine Combined with Hydromorphone Nasal Drip in Sedation of Mother-InfantSeparation before Adenoidectomy

Related Author

Duan Chenxia

Zhang Zuoliang

Gao Xiuxiu

Chen Yi

Wei Lei

Zhang

He Yang

Gao Rongrong

Related Institution

Suzhou Hospital Affiliated to Nanjing Medical University

Nanjing Children’s Hospital

Hengshui People’ sHospital, Hebei Hengshui

Shenzhou People’s Hospital, Hebei Shenzhou

China National Nuclear Corporation 404 Hospital

⁰