Clinical Analysis and Literature Review of Levofloxacin in the Treatment of Neonatal Burkholderia Cepacia Infection

Sun Chong; Li Yan; Ma Shuli

doi:10.13407/j.cnki.jpp.1672-108X.2020.11.010

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Clinical Analysis and Literature Review of Levofloxacin in the Treatment of Neonatal Burkholderia Cepacia Infection

更新时间：2022-11-03

- Clinical Analysis and Literature Review of Levofloxacin in the Treatment of Neonatal Burkholderia Cepacia Infection
- Vol. 26, Issue 11, Pages: 31-34(2020)
- 作者机构：
  
  郑州大学附属儿童医院，河南省儿童医院，郑州儿童医院,河南,郑州,450000
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2020.11.010
  CLC：
- Published：2020，
  
  Published Online：10 November 2020，
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Sun Chong, Li Yan, Ma Shuli. Clinical Analysis and Literature Review of Levofloxacin in the Treatment of Neonatal Burkholderia Cepacia Infection. [J]. 26(11):31-34(2020)
DOI：

Sun Chong, Li Yan, Ma Shuli. Clinical Analysis and Literature Review of Levofloxacin in the Treatment of Neonatal Burkholderia Cepacia Infection. [J]. 26(11):31-34(2020) DOI： 10.13407/j.cnki.jpp.1672-108X.2020.11.010.

摘要

目的：探讨临床药师在新生儿洋葱伯克霍尔德菌感染治疗中的作用。方法：回顾性分析临床药师参与1例左氧氟沙星治疗新生儿洋葱伯克霍尔德菌感染的病例。结果：临床药师通过对左氧氟沙星用于新生儿感染的风险和益处进行评估，参与抗感染方案的调整，经过综合治疗患儿呼吸较前好转，体温恢复正常，病情改善。结论：在充分评估风险获益后，氟喹诺酮类药物可用于治疗危及生命或难以治疗的感染儿童，有利于降低儿科患者洋葱伯克霍尔德菌重症感染的致死率。

Abstract

Objective: To probe into the role of clinical pharmacists in anti-infective treatment of neonatal Burkholderia cepacia infection. Methods: Retrospective analysis was performed on clinical pharmacists’ participation of levofloxacin in the treatment of neonatal Burkholderia cepacia infection. Results: Clinical pharmacists assessed the risks and benefits of levofloxacin for neonatal infection

and participated into the adjustment of anti-infective regimens. After comprehensive treatment

the child’s respiration was better than before

and the body temperature returned to the normal state. Conclusion: After fully assessing the risks and benefits

fluoroquinolones can be used to treat life-threatening or difficult-to-treat children with infections

which will help to reduce the mortality of pediatrics with severe Burkholderia cepacia infection.

关键词

左氧氟沙星洋葱伯克霍尔德菌新生儿

Keywords

levofloxacinBurkholderia cepacianeonates

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