A Case of Autoimmune Hemolytic Anemia Induced by Cefdinil Dispersible Tablets

Xiang Qiumei; Hu Wenjun

doi:10.13407/j.cnki.jpp.1672-108X.2020.07.015

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A Case of Autoimmune Hemolytic Anemia Induced by Cefdinil Dispersible Tablets

更新时间：2022-11-03

- A Case of Autoimmune Hemolytic Anemia Induced by Cefdinil Dispersible Tablets
- Vol. 26, Issue 7, Pages: 47-49(2020)
- 作者机构：
  
  北京市丰台区妇幼保健院,北京,100069
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2020.07.015
  CLC：
- Published：2020，
  
  Published Online：10 July 2020，
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Xiang Qiumei, Hu Wenjun. A Case of Autoimmune Hemolytic Anemia Induced by Cefdinil Dispersible Tablets. [J]. 26(7):47-49(2020)
DOI：

Xiang Qiumei, Hu Wenjun. A Case of Autoimmune Hemolytic Anemia Induced by Cefdinil Dispersible Tablets. [J]. 26(7):47-49(2020) DOI： 10.13407/j.cnki.jpp.1672-108X.2020.07.015.

摘要

目的：探讨头孢地尼分散片致自身免疫性溶血性贫血（AIHA）的诊断及治疗。方法：分析1例头孢地尼分散片致AIHA患者的诊疗经过，结合文献检索，探索头孢地尼分散片诱发AIHA的机制及应对措施。结果：患儿口服头孢地尼分散片1 d后发生AIHA，立即停用，给予注射用甲泼尼龙琥珀酸钠抑制免疫反应，5%碳酸氢钠碱化尿液、吸氧等对症治疗，并于停药后1周溶血得到控制。结论：儿童临床使用头孢地尼时，需密切关注患者是否有溶血临床表现，以便及时发现问题，及时采取适当的处理措施，以保证患者的用药安全

Abstract

Objective: To probe into the diagnosis and treatment of autoimmune hemolytic anemia (AIHA) induced by cefdinil dispersible tablets. Methods: The diagnosis and treatment of one child with AIHA induced by cefdinil dispersible tablets were analyzed. Combined with literature retrieval

the mechanism and countermeasures of AIHA induced by cefdinil dispersible tablets were explored. Results: After one day of oral administration of cefdinir dispersible tablets

AIHA occurred in the child. Cefdinir dispersible tablets was stopped immediately. Mepredronate sodium for injection was given to suppress the immune response

5% sodium bicarbonate alkalization of urine

oxygen inhalation and other symptomatic treatments were given

and hemolysis was controlled after drug withdrawal of one week. Conclusion: When cefdeni is used clinically in children

it is necessary to pay close attention to whether the child has clinical manifestations of hemolysis

so as to timely find out the problems and take appropriate treatment measures to ensure the safe medication

关键词

头孢地尼分散片不良反应自身免疫性溶血性贫血

Keywords

cefdinil dispersible tabletsadverse drug reactionsautoimmune hemolytic anemia

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