Reference Values of Serum 25-Hydroxy Vitamin D in Healthy Children Aged from 0 to 3 Years in Chongqing

Qu Lingling; Chen Liangwen; Zhong Yuanfeng; Zhang Xuan; Zhong Xiaoni; Li Hongxia; Liu Chuan; Zhou Guangqin; Huang Jian; Han Meiyan; Cheng Qian

doi:10.13407/j.cnki.jpp.1672-108X.2020.03.001

您当前的位置：

首页 >

文章列表页 >

Reference Values of Serum 25-Hydroxy Vitamin D in Healthy Children Aged from 0 to 3 Years in Chongqing

更新时间：2022-11-03

- Reference Values of Serum 25-Hydroxy Vitamin D in Healthy Children Aged from 0 to 3 Years in Chongqing
- Vol. 26, Issue 3, Pages: 1-4(2020)
- 作者机构：
  
  1. 重庆医科大学附属儿童医院，儿童发育疾病研究教育部重点实验室，国家儿童健康与疾病临床医学研究中心，儿童发育重大疾病国家国际科技合作基地，儿科学重庆市重点实验室,重庆,400014
  2. 重庆医科大学公共卫生学院,重庆,400016
  3. 重庆黔江区妇幼保健院,重庆,409000
  4. 重庆万州区妇幼保健院,重庆,404100
  5. 重庆渝北区妇幼保健院,重庆,401120
  6. 重庆云阳县妇幼保健院,重庆,404500
  7. 重庆江津区妇幼保健院,重庆,402260
- 作者简介：
- 基金信息：
- DOI：10.13407/j.cnki.jpp.1672-108X.2020.03.001
  CLC：
- Published：2020，
  
  Published Online：10 March 2020，
扫描看全文
Qu Lingling, Chen Liangwen, Zhong Yuanfeng, et al. Reference Values of Serum 25-Hydroxy Vitamin D in Healthy Children Aged from 0 to 3 Years in Chongqing. [J]. 26(3):1-4(2020)
DOI：

Qu Lingling, Chen Liangwen, Zhong Yuanfeng, et al. Reference Values of Serum 25-Hydroxy Vitamin D in Healthy Children Aged from 0 to 3 Years in Chongqing. [J]. 26(3):1-4(2020) DOI： 10.13407/j.cnki.jpp.1672-108X.2020.03.001.

摘要

目的：探讨重庆地区0~3岁儿童25-羟基维生素D（25OHD）的参考值。方法：选取代表重庆市不同经济水平的不同地域的区/县所在地医院儿保科进行正常体检儿童，按照纳入和排除标准，共纳入900例儿童，抽取静脉血，分离血清，采用高效液相色谱-质谱法（LC-MS）检测血清25OHD浓度，同时对每个调查对象进行体格检查及问卷调查。结果：重庆市0~3岁儿童外周血25OHD值参考值范围为（34.99±20.27）ng/mL。女童和男童25OHD水平差异无统计学意义（u=-1.327，P=0.185）；<1岁组儿童25OHD水平高于1~3岁组（u=2.062，P=0.040）；冬春季25OHD水平低于夏秋季（u=-4.299，P=0.000）。结论：重庆地区0～3岁婴幼儿25OHD的参考值范围为（34.99±20.27）ng/mL；健康婴幼儿不同年龄、不同季节的25OHD水平有一定差异；本研究得出的参考值范围与全球专家共识及美国IOM的推荐值基本一致，为婴幼儿期维生素D的补充及维生素D缺乏相关疾病的诊断提供客观依据。

Abstract

Objective: To probe into the reference values of 25-hydroxy vitamin D (25OHD) in healthy children aged from 0 to 3 years in Chongqing. Methods: According to inclusion and exclusion criteria

a total of 900 healthy children aged from 0 to 3 years with physical examination in child health care department of different hospital from districts/counties in different regions representing different economic levels of Chongqing were extracted. Venous blood was extracted

serum was separated

and serum 25OHD concentration was detected by high performance liquid chromatography-mass spectrometry (LC-MS). Physical examination and questionnaire survey were conducted for each respondent at the same time. Results: The reference values of serum 25OHD in children aged from 0 to 3 years in Chongqing was (34.99±20.27) ng/mL. There was no significant difference in the levels of 25OHD between girls and boys (u=-1.327

P=0.185). The levels of25OHD in the <1 year group were higher than those in the 1 to 3 year group (u=2.062

P=0.040). The levels of 25OHD in winter and spring were lower than those in summer and autumn (u=-4.299

P=0.000). Conclusion: The reference values of serum 25OHD in children aged from 0 to 3 years in Chongqing was (34.99±20.27) ng/mL. The 25OHD levels in healthy infants varied by age and season. The range of reference values obtained in this study is basically consistent with the global expert consensus and the recommended value of the IOM in the United States

which provides objective evidence for vitamin D supplementation and diagnosis of vitamin D deficiency-related diseases in infants.

关键词

25-羟基维生素D儿童参考值

Keywords

25-hydroxy vitamin Dchildrenreference values

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Analysis of 36 Cases of Drug Poisoning in Children in a Grade III, Level A General Hospital andConsideration on Pharmaceutical Care

Application of Dexmedetomidine Combined with Hydromorphone Nasal Drip in Sedation of Mother-InfantSeparation before Adenoidectomy

Sirolimus in the Treatment of 5 Cases of Blue Rubber Bleb Nevus Syndrome in Children and Literature Review

Systematic Review on Efficacy and Safety of Zoledronic Acid in the Treatment of Bone Metabolic Disordersin Children

Drug Utilization Evaluation of Voriconazole for Injection in Children Based on Weighted Technique for Order Preference by Similarity to Ideal Solution Method

Related Author

Wang Peng

Xu Ying

Zhang Xiaoming

Zhang Shaonan

Li Changsong

Li Yunxiang

Li Xiaojing

Sun Canlin

Related Institution

The Second People’ s Hospital of Anhui Wuhu, Anhui Wuhu

Jiangsu Taizhou People’s Hospital, Jiangsu Taizhou

Children’s Hospital Affiliated to Zhengzhou University,Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou Key Laboratory of Children’s Digestive Diseases

Kunming Children’s Hospital / Children’s Hospital of Kunming Medical University, Kunming

Kunming MedicalUniversity, Kunming

⁰